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Pulmonary Arterial Hypertension in Systemic Sclerosis

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified August 2009 by IRCCS Policlinico S. Matteo.
Recruitment status was:  Recruiting
Information provided by:
IRCCS Policlinico S. Matteo Identifier:
First received: February 6, 2008
Last updated: August 3, 2009
Last verified: August 2009
The purpose of this study is to evaluate the role of stress echocardiography, compared to standard echocardiography in the early identification of pulmonary arterial hypertension in systemic sclerosis. To evaluate the role of BNP in this setting.To analyze data recorded with respect to the parameters commonly used for SSc evaluation (eg thorax HRCT, pulmonary function tests + DLCO, nailfold capillaroscopy, etc); these parameters are available starting for 1999.

Systemic Sclerosis Pulmonary Arterial Hypertension

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Stress Echocardiography in the Early Identification of Pulmonary Arterial Hypertension in Systemic Sclerosis

Resource links provided by NLM:

Further study details as provided by IRCCS Policlinico S. Matteo:

Estimated Enrollment: 200
Study Start Date: December 2007
Estimated Study Completion Date: January 2010

Ages Eligible for Study:   18 Years to 90 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
patients with systemic sclerosis

Inclusion Criteria:

  • Patients with systemic sclerosis according to LeRoy criteria

Exclusion Criteria:

  • Pregnancy
  • Significant valvular disease
  • Low left ventricular function upon echocardiography (ejection fraction<55%)
  • History of atrial fibrillation, myocardial infarction, pulmonary thromboembolisms, neoplasia or severe hepatic disease.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00617487

Contact: Lorenzo Cavagna, MD 00390382501878

IRCCS Foundation Policlinico S. Matteo Recruiting
Pavia, PV, Italy, 27100
Contact: Lorenzo Cavagna, MD    00390382 ext 501878   
IRCCS Policlinico S. Matteo Recruiting
Pavia, PV, Italy, 27100
Principal Investigator: Stefano Ghio, MD         
Sponsors and Collaborators
IRCCS Policlinico S. Matteo
Study Director: Stefano Ghio, MD IRCCS Foundation Policlinico S. Matteo, Cardiology
Principal Investigator: Lorenzo Cavagna, MD University and IRCCS Foundation Policlinico S. Matteo, Rheumatology
  More Information

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: Dr Ghio Stefano, Cardiology Unit IRCCS Foundation Policlinico S. Matteo, Pavia Identifier: NCT00617487     History of Changes
Other Study ID Numbers: EchostressSSc
Study First Received: February 6, 2008
Last Updated: August 3, 2009

Additional relevant MeSH terms:
Familial Primary Pulmonary Hypertension
Scleroderma, Systemic
Scleroderma, Diffuse
Vascular Diseases
Cardiovascular Diseases
Pathologic Processes
Hypertension, Pulmonary
Lung Diseases
Respiratory Tract Diseases
Connective Tissue Diseases
Skin Diseases processed this record on August 23, 2017