Inheritance of Osteosarcoma & Paget's Disease Through Chromosome 18:
![]() |
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. |
ClinicalTrials.gov Identifier: NCT00615628 |
Recruitment Status
:
Terminated
(low enrollment low enrollment)
First Posted
: February 14, 2008
Last Update Posted
: May 30, 2013
|
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
Condition or disease |
---|
Osteosarcoma Paget's Disease |
Study Type : | Observational |
Actual Enrollment : | 8 participants |
Observational Model: | Family-Based |
Time Perspective: | Prospective |
Official Title: | Inheritance of Osteosarcoma & Paget's Disease Through Chromosome 18: Examination of Osteosarcoma Tissue Samples From Two Family Members for Loss of Heterozygosity in the Chromosome 18 Region, Genetically Linked With Paget's Disease of Bone |
Study Start Date : | April 2002 |
Actual Primary Completion Date : | December 2009 |
Actual Study Completion Date : | December 2009 |

Group/Cohort |
---|
family members
family members of the proband and father identified
|
- Loss of heterozygosity [ Time Frame: January, 2000 through February 2009 ]A loss of heterozygosity of a proposed tumor suppressor gene on chromosome 18
Biospecimen Retention: Samples With DNA

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Ages Eligible for Study: | Child, Adult, Senior |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Sampling Method: | Non-Probability Sample |
Inclusion Criteria:
- This is a familial study therefore the only inclusion/exclusion criteria would be that subjects must be a blood relative and over the age of 18.
- The subjects are proband and father along with unaffected blood relatives. Their peripheral blood will act as a control and provide information to delineate the inheritance from the father, as seen in the son.
Exclusion Criteria:
- Not part of the family

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00615628
United States, New York | |
SUNY Upstate Medical University | |
Syracuse, New York, United States, 13202 |
Principal Investigator: | Timothy A Damron, MD | State University of New York - Upstate Medical University |
Responsible Party: | Timothy Damron, M.D., Associate Professor, State University of New York - Upstate Medical University |
ClinicalTrials.gov Identifier: | NCT00615628 History of Changes |
Other Study ID Numbers: |
Osteosarcoma & Paget's Disease IRB #4168 ( Other Identifier: IRB number ) |
First Posted: | February 14, 2008 Key Record Dates |
Last Update Posted: | May 30, 2013 |
Last Verified: | May 2013 |
Keywords provided by Timothy Damron, M.D., State University of New York - Upstate Medical University:
Inheritance of Osteosarcoma & Paget's Disease through Chromosome 18 |
Additional relevant MeSH terms:
Osteosarcoma Neoplasms, Bone Tissue Neoplasms, Connective Tissue Neoplasms, Connective and Soft Tissue |
Neoplasms by Histologic Type Neoplasms Sarcoma |