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Environmental Pollutants and the Risk of Soft Tissue Sarcoma: A Pilot Study

This study has been completed.
Information provided by:
Memorial Sloan Kettering Cancer Center Identifier:
First received: January 25, 2008
Last updated: January 19, 2011
Last verified: January 2011
The purpose of this study is to assess the feasibility of conducting a large hospital based case control study of the role of dioxins and dioxinlike polychlorinated dibenzofurans (PCDFs) and polychlorinated biphenyls (PCBs).

Soft Tissue Sarcoma

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Environmental Pollutants and the Risk of Soft Tissue Sarcoma: A Pilot Study

Resource links provided by NLM:

Further study details as provided by Memorial Sloan Kettering Cancer Center:

Primary Outcome Measures:
  • enrollment of 60 participants [ Time Frame: Conclusion of the study ]

Biospecimen Retention:   Samples With DNA
blood, adipose tissue

Enrollment: 56
Study Start Date: September 2004
Study Completion Date: January 2011
Primary Completion Date: January 2011 (Final data collection date for primary outcome measure)

Ages Eligible for Study:   18 Years to 79 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Patients with Soft Tissue Sarcoma at Memorial Sloan Kettering Cancer Center.

Inclusion Criteria:

  • Patients with Soft tissue sarcoma at MSKCC are eligible for this study if they meet the following criteria:
  • Between 18 and 79 years of age
  • were diagnosed within the previous 6 months with primary soft tissue sarcoma of one of the following histologic subtypes: liposarcoma, leiomyoscaroma, MFH, or synovial sarcoma
  • are enrolled in protocol 02-060 ("Novel Biochemical and Molecularr Determinants for Soft Tissue Sarcoma"; PI, Dr. Samuel Singer)
  • controls will be eligibile for this study if they meet the following criteria
  • are b/w 18-79 years of age
  • have no prior history of cancer (other than non melanoma skin cancer)

Exclusion Criteria:

  • Individuals will be excluded if they
  • are unable to sign informed consent for medical or other reasons
  • do not speak english
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00611078

United States, New York
Memorial Sloan-Kettering Cancer Center
New York, New York, United States, 10021
Sponsors and Collaborators
Memorial Sloan Kettering Cancer Center
Principal Investigator: Lawrence Engel, Ph.D. Memorial Sloan Kettering Cancer Center
  More Information

Responsible Party: Engel, Lawrence Stuart, PhD, Memorial Sloan-Kettering Cancer Center Identifier: NCT00611078     History of Changes
Other Study ID Numbers: 04-088
Study First Received: January 25, 2008
Last Updated: January 19, 2011

Keywords provided by Memorial Sloan Kettering Cancer Center:
Soft Tissue Sarcoma

Additional relevant MeSH terms:
Neoplasms, Connective and Soft Tissue
Neoplasms by Histologic Type
Neoplasms processed this record on April 28, 2017