A Study To See If GSK256073A Can Block Niacin-Induced Flushing In Healthy Volunteers
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Layout table for eligibility information
Ages Eligible for Study:
18 Years to 55 Years (Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Adult males between 18 and 55 years of age, inclusive.
Body weight > 50 kg (110 pounds) and body mass index (BMI) between 19 and 31 where:
Subjects with QTc < 450 msec at screening
History of significant cardiac arrhythmias
Active peptic ulcer disease (PUD) and/or history of PUD
History of gout and/or hyperuricemia
History of Gilbert's syndrome
History of recurrent indigestion, stomach upset or diarrhea
History of other than rare (once yearly or less) flushing