A Comparison of Cognitive Processing Therapy (CPT) Versus Present Centered Therapy (PCT) for Veterans
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT00607815|
Recruitment Status : Active, not recruiting
First Posted : February 6, 2008
Results First Posted : July 20, 2015
Last Update Posted : September 5, 2017
|Condition or disease||Intervention/treatment||Phase|
|PTSD||Behavioral: Cognitive Processing Therapy Behavioral: Present Centered Therapy||Not Applicable|
The purpose of this study is to compare the effectiveness of Cognitive Processing Therapy (CPT) versus Present Centered Therapy (PCT) for male OEF/OIF Veterans with combat related PTSD.
CPT has been shown to be effective in treating trauma survivors in several treatment outcome studies, but utility with Veterans has only been examined with male Veterans in one small pilot study. In addition CPT has never been compared to a treatment as usual or supportive psychotherapy condition to control for the specific and nonspecific elements of treatment. Although Cognitive Processing Therapy is one of the main treatment modalities at several VA's, including Cincinnati, it has never been compared to PCT, nor has it been used in a large, randomized study of male OEF/OIF Veterans. It is hypothesized that individual receiving CPT will show a larger reduction in posttraumatic stress disorder and related symptoms than those individuals receiving PCT.
All male OEF/OIF Veterans will be screened for their appropriateness for the study by phone screen and then by an assessment technician. The Veteran will be assessed at pre, post, 3-month, and 1-year follow-up. The assessment technicians will be blind to the participant's condition. CPT is a 12 week long individual psychotherapy treatment shown to be effective at reducing PTSD and related symptoms for survivors of various types of traumas, including combat. PCT is a supportive counseling treatment that has been utilized as an alternative to waitlist control in VA cooperative studies of PTSD.
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||79 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Double (Investigator, Outcomes Assessor)|
|Official Title:||A Comparison of CPT vs PCT for Veterans|
|Actual Study Start Date :||June 15, 2009|
|Actual Primary Completion Date :||February 1, 2015|
|Estimated Study Completion Date :||December 27, 2017|
Active Comparator: Cognitive Processing Therapy
Cognitive Processing Therapy
Behavioral: Cognitive Processing Therapy
CPT is a highly structured protocol in which the client learns the skill of recognizing and challenging dysfunctional cognitions, first about the worst traumatic event and then later with regard to the meaning of the events for current beliefs about self and others.
Active Comparator: Present Centered Therapy
Present Centered Therapy
Behavioral: Present Centered Therapy
Present centered therapy is a supportive counseling model developed by Drs. Foa and Shea. The treatment is called "present centered therapy" to 1) emphasize the need to focus on the participant's current life and 2) to conceptualize the problems as being caused by PTSD, and in some cases they may have been present for a long period of time. The treatment makes a connection between PTSD and current problems thus making it a more realistic PTSD treatment and still allowing PCT to control for nonspecific therapeutic factors
- Clinician Administered PTSD Scale [ Time Frame: Post-treatment, at 3 months and 1 year ]Clinician-rated PTSD symptom severity; higher is worse; range at post-treatment is 0 to 80; scale scores are summed.
- PTSD Checklist (PCL) [ Time Frame: post-treatment, at 3 months and 1 year ]17-item patient self-reported PTSD severity; higher is worse; range at post-treatment is 17-73; scale scores are summed
- Beck Depression Inventory - II (BDI-II) [ Time Frame: post-treatment, at 3 months and 1 year ]Gold-standard, self-reported depression severity measure; higher is worse; post-treatment range is 2-45. scale scores are summed.
- State-Trait Anger Scale (STAXI) [ Time Frame: post-treatment, at 3 months and 1 year ]Self-reported trait anger; subscale score is summed; higher is worse; range at post-treatment is 10-37.
- State-Trait Anxiety Scale [ Time Frame: post-treatment, at 3 months and 1 year ]Self-reported state anxiety; higher is worse; scale score is summed; range at post-treatment is 20-73.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00607815
|United States, Ohio|
|Cincinnati VA Medical Center, Cincinnati, OH|
|Cincinnati, Ohio, United States, 45220|
|Principal Investigator:||Kathleen M Chard, PhD||Cincinnati VA Medical Center, Cincinnati, OH|