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Effect of Nutrition on Muscle Protein Synthesis

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00604929
First Posted: January 30, 2008
Last Update Posted: April 14, 2015
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Milou Beelen, Maastricht University Medical Center
  Purpose
The present proposal is designed to examine the effect of carbohydrate and protein co-ingestion on muscle protein synthesis during endurance type exercise activities. We hypothesize that muscle protein synthesis is higher when protein is co-ingested during exercise.

Condition Intervention
Healthy Dietary Supplement: carbohydrate and protein

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Double (Participant, Investigator)
Primary Purpose: Basic Science
Official Title: The Effect of Carbohydrate and Protein Intake on Muscle Protein Synthesis During Endurance Exercise

Further study details as provided by Milou Beelen, Maastricht University Medical Center:

Primary Outcome Measures:
  • Differences in muscle protein synthesis rates between carbohydrate and carbohydrate + protein. [ Time Frame: 1 day ]

Secondary Outcome Measures:
  • Difference in whole-body protein synthesis and breakdown between carbohydrate and carbohydrate plus protein. [ Time Frame: 1 day ]

Enrollment: 12
Study Start Date: August 2008
Study Completion Date: February 2009
Primary Completion Date: February 2009 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: 1 Dietary Supplement: carbohydrate and protein
The intake of carbohydrate and protein during endurance type exercise

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 28 Years   (Adult)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • recreationally endurance trained

Exclusion Criteria:

  • BMI > 25 kg/m2
  • Not physically active
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00604929


Sponsors and Collaborators
Maastricht University Medical Center
Investigators
Principal Investigator: L van Loon, PhD Maastricht University
  More Information

Responsible Party: Milou Beelen, Dr., Maastricht University Medical Center
ClinicalTrials.gov Identifier: NCT00604929     History of Changes
Other Study ID Numbers: MEC 83017
First Submitted: January 17, 2008
First Posted: January 30, 2008
Last Update Posted: April 14, 2015
Last Verified: April 2015

Keywords provided by Milou Beelen, Maastricht University Medical Center:
muscle protein synthesis
whole-body protein breakdown
nutrition