Oral Care Protocol for Preventing Ventilator- Associated Pneumonia (VAP)
|ClinicalTrials.gov Identifier: NCT00604916|
Recruitment Status : Completed
First Posted : January 30, 2008
Last Update Posted : January 30, 2008
The Nosocomial Pneumonia remains to be a major complication for patients who were incubated with ventilation. Most cases are attributed to increased bacteria flora in oropharyngeal secretion and aspiration of those organisms. Research indicates that the Gram-Negative Bacteria grows in upper air way and trachea rapidly during the initial 2-4 hospital days and the dental plague also increased dramatically at the first 5 days. About 50% cases with prolonged intubation experienced temporal swallowing disorders and majority of them recovered 7 days post weaning. Some evidence exist suggesting that oral care could reduce bacterial flora, prevent aspiration, and subsequently decrease the incidence of ventilation-associated pneumonia for this group of high risk patients.
This study aims to evaluate the effectiveness of a standardized oral care protocol in improving oral hygiene and reducing the incidence of pneumonia on a sample of surgical patients at intensive care unit.
|Condition or disease||Intervention/treatment||Phase|
|Pneumonia||Other: standardized oral care protocol - electronic toothbrush Other: mimic protocol||Early Phase 1|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||53 participants|
|Intervention Model:||Parallel Assignment|
|Official Title:||The Effectiveness of an Oral Care Protocol in Preventing Ventilator- Associated Pneumonia for Intensive Care Unit Patient|
|Study Start Date :||March 2007|
|Actual Primary Completion Date :||November 2007|
|Actual Study Completion Date :||January 2008|
received a 7 day standardized oral care protocol
Other: standardized oral care protocol - electronic toothbrush
a standardized 20-minute oral care protocol using an electronic toothbrush to clean and moisturize oral cavity twice daily.
Placebo Comparator: C
received a 7 day mimic protocol
Other: mimic protocol
a mimic 20-minute protocol involving moisturizing and attention control was performed for the same intervals.
- the oral hygiene status measured by the oral assessment guide and plague index [ Time Frame: every 3~4days ]
- The incidence of VAP defined by the Clinical Pulmonary Infection Score [ Time Frame: a 7 day oral care protocol duration ]
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00604916
|Principal Investigator:||li-yin YAO, BSN||School of Nursing, National Taiwan University|