This site became the new on June 19th. Learn more.
Show more Menu IMPORTANT: Listing of a study on this site does not reflect endorsement by the National Institutes of Health. Talk with a trusted healthcare professional before volunteering for a study. Read more... Menu IMPORTANT: Talk with a trusted healthcare professional before volunteering for a study. Read more... Menu
Give us feedback

Incidence of Delirium in Critically Ill Patients in a Dutch University Hospital

This study has been completed.
Information provided by:
Radboud University Identifier:
First received: January 17, 2008
Last updated: August 30, 2010
Last verified: February 2009

The objective of this study is to determine the incidence of delirium in adults patients who are admitted at the critical care unit of a Dutch University Hospital.

The primary aim is to determine the incidence of delirium and to determine risk factors for this group of patients to develop a prediction model.

A secondary aim is to find differences between delirious patients and non-delirious patients on different aspects of diagnostics, treatment and care, outcome, length of stay, and inflammation.

According to Dutch law, the need to obtain informed consent was waived by the Committee on Research Involving Human Subjects (CMO) of Nijmegen for this observational study (2007/283).


Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Incidence of Delirium in Critically Ill Patients in a Dutch University Hospital

Resource links provided by NLM:

Further study details as provided by Radboud University:

Primary Outcome Measures:
  • delirium [ Time Frame: during admission at the critical care ]

Secondary Outcome Measures:
  • markers of inflammation [ Time Frame: within 24 hours of delirium diagnosis ]
  • biomarkers [ Time Frame: within 24 hours of delirium diagnosis ]

Biospecimen Retention:   Samples With DNA
blood, urine

Estimated Enrollment: 700
Study Start Date: February 2008
Study Completion Date: February 2009
Primary Completion Date: February 2009 (Final data collection date for primary outcome measure)
delirious patients
minimal one positive CAM-ICU score during ICU admission
non-delirious patients
without any positive CAM-ICU scores during ICU admission


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
tertiary care clinic

Inclusion Criteria:

  • all adult patients (18 years and older) admitted at the critical care unit of our hospital

Exclusion Criteria:

  • not able to understand Dutch
  • patients with serious hearing and visibility disabilities
  • mentally retarded patients
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00604773

Radboud University Nijmegen Medical Centre, Critical Care
Nijmegen, Gelderland, Netherlands, 6500
Sponsors and Collaborators
Radboud University
Principal Investigator: Hans vd Hoeven, MD, PhD Radboud University
  More Information

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: M. van den Boogaard, MSc, RN, CCRN, Radboud University Nijmegen Medical Centre Identifier: NCT00604773     History of Changes
Other Study ID Numbers: Radboud 2007/283
Study First Received: January 17, 2008
Last Updated: August 30, 2010

Keywords provided by Radboud University:
critical care
risk factors

Additional relevant MeSH terms:
Critical Illness
Disease Attributes
Pathologic Processes
Neurobehavioral Manifestations
Neurologic Manifestations
Nervous System Diseases
Signs and Symptoms
Neurocognitive Disorders
Mental Disorders processed this record on September 21, 2017