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Cardiac AResT And GENEtic (CARTAGENE)

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00604149
First Posted: January 30, 2008
Last Update Posted: June 25, 2015
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Institut National de la Santé Et de la Recherche Médicale, France
  Purpose
Sudden death is a major problem in industrially developed countries. Despite a decline in ischemic heart disease mortality and the progress has been made in resuscitation, treatment of sudden death victims is frequently unsuccessful. the ideal solution would be to prevent the disease process that causes the initial episode of cardiac arrest. Parental sudden death is an independent risk factor for sudden death. So, detect a gene predisposing to sudden death may help provide better identification of subjects at high risk of cardiac arrest. This research is a genetic study of sudden cardiac death, recruited 2000 subjects in out-of-hospital cardiac arrest.

Condition
Out-of-hospital Cardiac Arrest

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Etude Multicentrique en Population de la susceptibilité génétique à Faire Une Mort Subite

Resource links provided by NLM:


Further study details as provided by Institut National de la Santé Et de la Recherche Médicale, France:

Biospecimen Retention:   Samples With DNA
whole blood to obtain DNA

Enrollment: 2332
Study Start Date: January 2008
Study Completion Date: January 2014
Primary Completion Date: January 2014 (Final data collection date for primary outcome measure)
Groups/Cohorts
1
case of out-of-hospital cardiac arrest
2
cases of MI
3
controls without coronary disease

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 75 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
all subjects in out-of-hospital cardiac arrest and treated by medical mobil emergency medical care
Criteria

Inclusion Criteria:

  • OHCA
  • Aged from 18 to 75 years

Exclusion Criteria:

  • Pregnant
  • People not free
  • Inhospital subjects
  • Death by other disease
  • Violent death
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00604149


Locations
France
Hôpital Européen Georges Pompidou
Paris, France, 75015
Sponsors and Collaborators
Institut National de la Santé Et de la Recherche Médicale, France
Investigators
Principal Investigator: Xavier Jouven, PhD, MD Institut National de la Santé Et de la Recherche Médicale, France
  More Information

Responsible Party: Institut National de la Santé Et de la Recherche Médicale, France
ClinicalTrials.gov Identifier: NCT00604149     History of Changes
Other Study ID Numbers: C07-35
2007-A01048-45 ( Registry Identifier: IDRCB )
First Submitted: January 16, 2008
First Posted: January 30, 2008
Last Update Posted: June 25, 2015
Last Verified: June 2015

Additional relevant MeSH terms:
Heart Arrest
Out-of-Hospital Cardiac Arrest
Heart Diseases
Cardiovascular Diseases