Effects of Lumbosacral Joint Mobilization/Manipulation on Lower Extremity Muscle Neuromuscular Response
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|ClinicalTrials.gov Identifier: NCT00601341|
Recruitment Status : Terminated (Anticipated that results would not be conclusive)
First Posted : January 28, 2008
Last Update Posted : June 24, 2010
The purpose of this study is to gain a better understanding of the effects of lumbopelvic manual therapy on lower extremity biomechanics and arthrogenic muscle response. As a result of this study, we also hope that physical therapists, athletic trainers, and other physical medicine rehabilitation providers will gain a better understanding of lower extremity injuries and have the scientific evidence to provide patients with techniques which would allow for efficient return to activities of daily living without restrictions and possibly prevent future injuries and minimize risk of osteoarthritis.
The objectives of this study are to:
- Determine the amount and duration of arthrogenic muscle response of quadriceps muscles following lumbopelvic joint manipulation.
- Determine the effects of lumbopelvic joint manipulation on temporospatial parameters of gait such cadence, step length, velocity and mean peak lower extremity joint moments.
- Determine if a correlation exists between patellofemoral joint pain and lumbopelvic joint dysfunction.
- Determine the amount of change in clinical outcome measure scores following lumbopelvic joint manipulation.
|Condition or disease||Intervention/treatment||Phase|
|Knee Pain Hip Pain Ankle Pain Lumbopelvic Pain||Other: lumbosacral joint manipulation Other: lumbar passive range of motion Other: No active intervention||Not Applicable|
It is well known that musculoskeletal dysfunction at one joint is not limited to the joint itself and can be related to dysfunction at joints proximal or distal in the kinetic chain. Recent research has focused on the relationship of altered lower extremity kinematics and common musculoskeletal pathologies.
Pain is often associated with musculoskeletal pathologies and is one of the strongest stimuli affecting functional activities in a negative manner. Following injury or chronic dysfunction, inhibitory neurons decrease the ability of musculature to fully recruit excitatory motor neurons. This can lead to aberrant movement patterns and different activation of muscles. Muscle inhibition has been attributed as a possible source of altered motor activation patterns. Pain can be a result or cause of musculoskeletal dysfunction and does not necessarily precede inhibition, but can have a contributing effect. The presence of muscle inhibition is considered a limiting factor in the rehabilitation of musculoskeletal pathologies. If muscle inhibition is properly addressed, individuals and athletes alike, should be able to more appropriately meet the demands of the activities with a decreased risk of future injury.
One technique used to determine presence of muscle inhibition is to measure the ability of the muscle to produce a maximal voluntary isometric contraction and compare values with the ability of the contralateral muscle. Since the contralateral limb may also experience muscle inhibition,it is difficult to obtain an accurate measurement of the amount of muscle inhibition occurring in the ipsilateral limb. A suggested solution is utilize the burst-superimposition technique which provides the muscle with a supramaximal stimulus to recruit any remaining muscle fibers which have not been stimulated.
Treatment of muscle inhibition is multifaceted. Utilization of manual therapy techniques such as joint manipulation or mobilization directed at the lumbopelvic region have been shown to be successful in disinhibiting lower extremity muscles. Previous studies have demonstrated sacroiliac joint manipulation disinhibited the quadriceps muscle in individuals with anterior knee pain. One of the limitations was these studies only observed an immediate decrease of quadriceps inhibition and the duration of the treatment effect was unknown. Effects of disinhibition of other lower extremity muscles and duration of disinhibition have not been determined at this time. It is also unknown what effects manual therapy treatments directed at the lumbopelvic region have on functional activities such as walking, squatting, or ascending/descending stairs. By examining these effects, we will be attempting to provide scientific evidence to validate common clinical practices in rehabilitative medicine.
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||106 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Official Title:||Effects of Lumbosacral Joint Mobilization/Manipulation on Lower Extremity Muscle Neuromuscular Response|
|Study Start Date :||May 2005|
|Estimated Primary Completion Date :||May 2009|
|Actual Study Completion Date :||November 2009|
lumbosacral joint manipulation
Other: lumbosacral joint manipulation
lumbosacral joint manipulation
lumbar passive range of motion
Other: lumbar passive range of motion
lumbar passive range of motion
lie on exam table for 3 minutes
Other: No active intervention
Lie on exam table for 3 minutes
- Neuromuscular response (central activation ratio), characteristics of gait (stride length, step length, etc.), joint moments [ Time Frame: All study visits up to day 21 ]
- Characteristics of gait (stride length, step length, etc.) [ Time Frame: All study visits up to day 21 ]
- Orthopedic special tests and questionnaires [ Time Frame: Concluding at day 21 ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00601341
|United States, Virginia|
|University of Virginia|
|Charlottesville, Virginia, United States, 22908|
|Principal Investigator:||Christopher Ingersoll, PhD||University of Virginia|