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A Simple Clinical Tool to Help Assess Patient Volume (Fluid) Status

This study has been completed.
Abbott Northwestern Hospital
Information provided by:
Mayo Clinic Identifier:
First received: January 11, 2008
Last updated: January 23, 2008
Last verified: January 2008
Patients may have actual or relative intravascular volume depletion in a number of different disease states, particularly with sepsis syndrome. However, it is clinically difficult to determine volume status without invasive monitoring, which may cause unintended complications. Our hypothesis is that we can accurately estimate central venous pressure, which is a surrogate marker of volume status, with a noninvasive portable ultrasound device.


Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: A Simple Clinical Tool to Help Assess Patient Volume (Fluid) Status

Resource links provided by NLM:

Further study details as provided by Mayo Clinic:

Enrollment: 84
Study Start Date: January 2006
Study Completion Date: January 2008
Primary Completion Date: October 2007 (Final data collection date for primary outcome measure)
Healty volunteers who are euvolemic.
Critically ill patients who will be having a central venous catheter with a monitor to measure central venous pressure placed as part of their planned care independent of this study.


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Healthy volunteers, then critically ill patients already in the intensive care unit who are felt to have intravascular volume depletion.

Inclusion Criteria:

  • Age 18 or older.
  • Healthy, euvolemic volunteers and critically ill patients who are already in an intensive care unit and who will have a central venous catheter placed as part of their planned medical treatment.

Exclusion Criteria:

  • Inability to use ultrasound to measure jugular vein (neck brace or bandage), "code" situation.
  Contacts and Locations
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Please refer to this study by its identifier: NCT00599794

United States, Minnesota
Abbott Northwestern Hospital
Minneapolis, Minnesota, United States, 55407
Mayo Clinic
Rochester, Minnesota, United States, 55905
Sponsors and Collaborators
Mayo Clinic
Abbott Northwestern Hospital
Principal Investigator: A. S. Keller, MD Mayo Clinic
  More Information

Additional Information:
Responsible Party: A. Scott Keller, Mayo Clinic Identifier: NCT00599794     History of Changes
Other Study ID Numbers: 05-004138
Study First Received: January 11, 2008
Last Updated: January 23, 2008

Keywords provided by Mayo Clinic:
Intravascular volume
Noninvasive measurement

Additional relevant MeSH terms:
Systemic Inflammatory Response Syndrome
Pathologic Processes processed this record on September 19, 2017