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Acupuncture for Infectious Mononucleosis Trial (AIM)

This study has been completed.
Information provided by:
University of Alberta Identifier:
First received: December 4, 2007
Last updated: January 8, 2009
Last verified: January 2009
The purpose of this study is to investigate feasibility issues related to conducting an acupuncture study in a population of adolescents and young adults with infectious mononucleosis. Additionally, this study will provide preliminary data regarding treatment parameters (acupuncture and standard care) and outcomes (i.e. fatigue).

Condition Intervention Phase
Infectious Mononucleosis Procedure: traditional Chinese acupuncture Other: standard medical care Phase 2 Phase 3

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Investigator)
Primary Purpose: Treatment
Official Title: Acupuncture for Infectious Mononucleosis Trial

Resource links provided by NLM:

Further study details as provided by University of Alberta:

Primary Outcome Measures:
  • Chalder Fatigue Questionnaire [ Time Frame: 12 weeks ]

Secondary Outcome Measures:
  • MOS SF-36 [ Time Frame: 12 weeks ]

Estimated Enrollment: 36
Study Start Date: January 2008
Study Completion Date: December 2008
Primary Completion Date: December 2008 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: A
Traditional Chinese acupuncture in conjunction with standard medical care
Procedure: traditional Chinese acupuncture
10 treatments over 6 weeks
Active Comparator: B
standard medical care
Other: standard medical care
standard care as provided by primary physician


Ages Eligible for Study:   15 Years to 25 Years   (Child, Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • mono diagnosis confirmed by lab test
  • 21 days or less between start of symptoms and diagnostic test
  • presence of fatigue of at least 4/11 (by Chalder Fatigue Questionnaire)
  • no other illnesses present
  • meets residency requirement

Exclusion Criteria:

  • insufficient communication in English
  • unable to begin acupuncture within 21 days of diagnostic test
  • acupuncture use currently or in the preceding 3 months
  • currently under the care of a TCM practitioner
  • unwilling to be randomized
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00598988

Canada, Alberta
University of Alberta
Edmonton, Alberta, Canada, T6G 2E1
Sponsors and Collaborators
University of Alberta
Principal Investigator: Sunita Vohra, MD, MSc University of Alberta
  More Information

Responsible Party: Sunita Vohra/Dr, University of Alberta Identifier: NCT00598988     History of Changes
Other Study ID Numbers: 6866
Study First Received: December 4, 2007
Last Updated: January 8, 2009

Keywords provided by University of Alberta:
infectious mononucleosis, mono, acupuncture

Additional relevant MeSH terms:
Communicable Diseases
Infectious Mononucleosis
Epstein-Barr Virus Infections
Herpesviridae Infections
DNA Virus Infections
Virus Diseases
Leukocyte Disorders
Hematologic Diseases
Lymphoproliferative Disorders
Lymphatic Diseases
Immunoproliferative Disorders
Immune System Diseases processed this record on August 17, 2017