Prevalence of Pituitary Incidentaloma in Relatives of Patients With Pituitary Adenoma

The recruitment status of this study is unknown because the information has not been verified recently.
Verified December 2010 by Cedars-Sinai Medical Center.
Recruitment status was  Recruiting
Information provided by:
Cedars-Sinai Medical Center Identifier:
First received: January 11, 2008
Last updated: December 14, 2010
Last verified: December 2010
The purpose of the study is to determine genetic links among blood-relatives and between spouses of patients with pituitary tumors.

Pituitary Tumor

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Prevalence of Pituitary Incidentaloma in Relatives of Patients With Pituitary Adenoma

Resource links provided by NLM:

Further study details as provided by Cedars-Sinai Medical Center:

Biospecimen Retention:   Samples With DNA
cell lines are established for future genetic analysis

Estimated Enrollment: 600
Study Start Date: January 2003
Estimated Primary Completion Date: December 2015 (Final data collection date for primary outcome measure)
Detailed Description:
The purpose of the family study is to investigate the genetic basis for the development of pituitary tumors by assessing the prevalence of pituitary tumors in relatives of probands with the disease as compared to the prevalence in unrelated spouses sharing a similar environment.

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
tertiary referral center

Inclusion Criteria:

  • patients harboring secretory or non-secretory adenomas and/or siblings and/or spouses

Exclusion Criteria:

  • patient without consenting siblings and/or siblings and/or spouses
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00598949

Contact: Billy Gellepis 310-423-3395
Contact: Lori korsakoff, RN 310-423-2411

United States, California
Cedars-Sinai Medical Center, Pituitary Center Recruiting
Los Angeles, California, United States, 90048
Contact: Vivien Bonert, MD    310-423-2830   
Contact: Lori Korsakoff, RN    310-423-2411   
Sponsors and Collaborators
Cedars-Sinai Medical Center
Principal Investigator: Vivian Bonert, MD Cedars-Sinai Medical Center
  More Information

Responsible Party: Vivien Bonert, MD, Cedars-Sinai Medical Center, Pituitary Center Identifier: NCT00598949     History of Changes
Other Study ID Numbers: 3765 
Study First Received: January 11, 2008
Last Updated: December 14, 2010
Health Authority: United States: Institutional Review Board

Keywords provided by Cedars-Sinai Medical Center:

Additional relevant MeSH terms:
Pituitary Diseases
Pituitary Neoplasms
Brain Neoplasms
Central Nervous System Neoplasms
Endocrine Gland Neoplasms
Hypothalamic Neoplasms
Neoplasms by Site
Nervous System Neoplasms
Supratentorial Neoplasms
Brain Diseases
Central Nervous System Diseases
Endocrine System Diseases
Hypothalamic Diseases
Nervous System Diseases processed this record on May 24, 2016