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Bedside Ultrasound Measurement of the Inferior Vena Cava Correlates to Central Venous Pressure

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ClinicalTrials.gov Identifier: NCT00596921
Recruitment Status : Unknown
Verified January 2008 by Brooke Army Medical Center.
Recruitment status was:  Not yet recruiting
First Posted : January 17, 2008
Last Update Posted : January 17, 2008
Information provided by:

Study Description
Brief Summary:
This study proposes to examine the correlation of central venous pressure to measures of the diameter of the inferior vena cava as determined by bedside ultrasonography.

Condition or disease
Shock Hypovolemia Hypervolemia

Detailed Description:
Central venous pressure (CVP) is a key physiologic estimate of preload, which in turn helps define the vascular fluid status. It is a particularly important parameter to measure in critically ill and injured patients who may require resuscitation. Unfortunately, measurement of the CVP requires invasive central venous catheters which can be difficult or time-consuming to insert. A non-invasive means of inferring the CVP would provide clinicians with an alternative. Preliminary data suggests that the diameter of the vena cava may reflect the CVP. Ultrasonography can provide reliable measures of internal body structures including the vena cava, and therefore may be useful in this regard. Collecting simultaneous values of vena cava diameter and CVPs will allow for the identification and quantification of correlation.

Study Design

Study Type : Observational
Estimated Enrollment : 100 participants
Observational Model: Case-Only
Time Perspective: Cross-Sectional
Official Title: Bedside Ultrasound Measurement of the Inferior Vena Cava Correlates to Central Venous Pressure

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Ultrasound
U.S. FDA Resources

Groups and Cohorts

Outcome Measures

Primary Outcome Measures :
  1. Bedside ultrasound measurement of the diameter of the inferior vena cava and simultaneously measured central venous pressure. [ Time Frame: Cross-sectional ]

Secondary Outcome Measures :
  1. Anatomic view and phase of respiration at the time of measurements. [ Time Frame: Cross-sectional ]

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Hospitalized patients with central venous monitoring in place.

Inclusion Criteria:

  • CVP or right heart catheter that is already in place and functioning properly

Exclusion Criteria:

  • Supine position or placement of ultrasound probe on abdomen is contraindicated.
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00596921

Contact: Robert A De Lorenzo, MD 210.916.0607

Sponsors and Collaborators
Brooke Army Medical Center
Principal Investigator: Robert A De Lorenzo, MD Brooke Army Medical Center
More Information

Responsible Party: COL Robert De Lorenzo, Brooke Army Medical Center
ClinicalTrials.gov Identifier: NCT00596921     History of Changes
Other Study ID Numbers: C.2008.029
First Posted: January 17, 2008    Key Record Dates
Last Update Posted: January 17, 2008
Last Verified: January 2008

Keywords provided by Brooke Army Medical Center:
Central Venous Pressure
Noninvasive monitoring

Additional relevant MeSH terms:
Pathologic Processes