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Bedside Ultrasound Measurement of the Inferior Vena Cava Correlates to Central Venous Pressure

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified January 2008 by Brooke Army Medical Center.
Recruitment status was:  Not yet recruiting
Information provided by:
Brooke Army Medical Center Identifier:
First received: January 8, 2008
Last updated: January 16, 2008
Last verified: January 2008
This study proposes to examine the correlation of central venous pressure to measures of the diameter of the inferior vena cava as determined by bedside ultrasonography.


Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Cross-Sectional
Official Title: Bedside Ultrasound Measurement of the Inferior Vena Cava Correlates to Central Venous Pressure

Resource links provided by NLM:

Further study details as provided by Brooke Army Medical Center:

Primary Outcome Measures:
  • Bedside ultrasound measurement of the diameter of the inferior vena cava and simultaneously measured central venous pressure. [ Time Frame: Cross-sectional ]

Secondary Outcome Measures:
  • Anatomic view and phase of respiration at the time of measurements. [ Time Frame: Cross-sectional ]

Estimated Enrollment: 100
Detailed Description:
Central venous pressure (CVP) is a key physiologic estimate of preload, which in turn helps define the vascular fluid status. It is a particularly important parameter to measure in critically ill and injured patients who may require resuscitation. Unfortunately, measurement of the CVP requires invasive central venous catheters which can be difficult or time-consuming to insert. A non-invasive means of inferring the CVP would provide clinicians with an alternative. Preliminary data suggests that the diameter of the vena cava may reflect the CVP. Ultrasonography can provide reliable measures of internal body structures including the vena cava, and therefore may be useful in this regard. Collecting simultaneous values of vena cava diameter and CVPs will allow for the identification and quantification of correlation.

Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Hospitalized patients with central venous monitoring in place.

Inclusion Criteria:

  • CVP or right heart catheter that is already in place and functioning properly

Exclusion Criteria:

  • Supine position or placement of ultrasound probe on abdomen is contraindicated.
  Contacts and Locations
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Please refer to this study by its identifier: NCT00596921

Contact: Robert A De Lorenzo, MD 210.916.0607

Sponsors and Collaborators
Brooke Army Medical Center
Principal Investigator: Robert A De Lorenzo, MD Brooke Army Medical Center
  More Information

Responsible Party: COL Robert De Lorenzo, Brooke Army Medical Center Identifier: NCT00596921     History of Changes
Other Study ID Numbers: C.2008.029
Study First Received: January 8, 2008
Last Updated: January 16, 2008

Keywords provided by Brooke Army Medical Center:
Central Venous Pressure
Noninvasive monitoring

Additional relevant MeSH terms:
Pathologic Processes processed this record on April 28, 2017