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Hyperbaric Oxygen Therapy and SPECT Brain Imaging in Carbon Monoxide Poisoning

This study is currently recruiting participants.
Verified April 2017 by Paul G. Harch, M.D., Louisiana State University Health Sciences Center in New Orleans
Sponsor:
ClinicalTrials.gov Identifier:
NCT00596180
First Posted: January 16, 2008
Last Update Posted: April 18, 2017
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.
Collaborator:
Harch Hyperbaric Research Foundation
Information provided by (Responsible Party):
Paul G. Harch, M.D., Louisiana State University Health Sciences Center in New Orleans
  Purpose
That SPECT brain imaging tracks and is consistent with clinical history and physical exam as well as cognitive testing.

Condition Intervention
Neuropsychiatric Sequelae of Carbon Monoxide Poisoning Drug: HBOT

Study Type: Observational
Study Design: Observational Model: Other
Time Perspective: Retrospective
Official Title: Hyperbaric Oxygen Therapy and SPECT Brain Imaging in Carbon Monoxide Poisoning

Resource links provided by NLM:


Further study details as provided by Paul G. Harch, M.D., Louisiana State University Health Sciences Center in New Orleans:

Primary Outcome Measures:
  • SPECT brain imaging [ Time Frame: after completion of HBOT ]

Secondary Outcome Measures:
  • clinical history and physical exam [ Time Frame: after completion of HBOT ]
  • Neuropsychological testing [ Time Frame: After the final HBOT ]
    Neuropsychological testing performed after the final HBOT in those who had neuropsychological testing before HBOT


Estimated Enrollment: 40
Study Start Date: January 2007
Estimated Study Completion Date: December 2019
Estimated Primary Completion Date: December 2018 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
1
HBOT
Drug: HBOT
total body exposure to greater than atmospheric pressure oxygen

Detailed Description:
The study is a retrospective review of the PI's experience using SPECT brain imaging and hyperbaric oxygen therapy in the diagnosis and treatment of non-acute phases of carbon monoxide poisoning. The purpose is to see if the SPECT brain imaging is consistent with the clinical condition and cognitive testing on the patients.
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Adults and children with non-acute carbon monoxide poisoning who underwent SPECT brain imaging as part of their evaluation and treatment. Retrospective chart review
Criteria

Inclusion Criteria:

  • Adults and children with non-acute carbon monoxide poisoning who underwent SPECT brain imaging as part of their evaluation and treatment

Exclusion Criteria:

  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00596180


Contacts
Contact: Paul G Harch, M.D. 504-309-4948 paulharchmd@gmail.com

Locations
United States, Louisiana
Family Physicians Center Recruiting
Marrero, Louisiana, United States, 70072
Contact: Paul G Harch, M.D.    504-309-4948    paulharchmd@gmail.com   
Principal Investigator: Paul G Harch, M.D.         
Sponsors and Collaborators
Paul G. Harch, M.D.
Harch Hyperbaric Research Foundation
Investigators
Principal Investigator: Paul G Harch, M.D. LSU School of Medicine
  More Information

Responsible Party: Paul G. Harch, M.D., Clinical Professor of Medicine, Louisiana State University Health Sciences Center in New Orleans
ClinicalTrials.gov Identifier: NCT00596180     History of Changes
Other Study ID Numbers: LSU IRB #6626
First Submitted: January 4, 2008
First Posted: January 16, 2008
Last Update Posted: April 18, 2017
Last Verified: April 2017
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

Keywords provided by Paul G. Harch, M.D., Louisiana State University Health Sciences Center in New Orleans:
carbon monoxide poisoning
brain injury

Additional relevant MeSH terms:
Poisoning
Carbon Monoxide Poisoning
Chemically-Induced Disorders
Gas Poisoning
Carbon Monoxide
Antimetabolites
Molecular Mechanisms of Pharmacological Action
Gasotransmitters
Neurotransmitter Agents
Physiological Effects of Drugs