Low-Dose Ketamine Infusion for Children With Sickle Cell Disease-Related Pain
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|ClinicalTrials.gov Identifier: NCT00595530|
Recruitment Status : Terminated (Lack of enrollment and patient interest in study)
First Posted : January 16, 2008
Results First Posted : March 30, 2016
Last Update Posted : March 30, 2016
|Condition or disease||Intervention/treatment||Phase|
|Sickle Cell Disease||Drug: ketamine||Phase 2|
Show Detailed Description
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||3 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||Use of Low-Dose Ketamine Infusion in Acute Painful Episodes of Sickle Cell Disease: A Pilot Study|
|Study Start Date :||January 2008|
|Actual Primary Completion Date :||June 2011|
|Actual Study Completion Date :||June 2011|
This group will receive ketamine
Medication administered via IV. This study will utilize 4 doses of ketamine: 0.05 mg/kg/hr, 0.1 mg/kg/hr, 0.15 mg/kg/hr, and 0.2 mg/kg/hr.
Patient may receive ketamine up to 72 hrs after initiation.
Other Name: Ketalar
- The Number of Participants That Experience Side Effects [ Time Frame: Daily while inpatient and once a week for first 4 weeks post discharge ]How many participants experienced side effects while undergoing treatment with the study drug?
- Intravenous Opiate Utilization [ Time Frame: Every 4 hours ]
- Self-reported Pain Scores [ Time Frame: Every 4 hours ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00595530
|United States, Connecticut|
|University of Connecticut Health Center|
|Farmington, Connecticut, United States, 06030|
|Connecticut Children's Medical Center|
|Hartford, Connecticut, United States, 06106|
|Principal Investigator:||William T Zempsky, MD||Connecticut Children's Medical Center|