MRI to Measure Liver Fat Content
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT00594412|
Recruitment Status : Completed
First Posted : January 15, 2008
Last Update Posted : July 2, 2017
This study will determine whether a magnetic resonance imaging (MRI) test of the liver can accurately measure the amount of fat in the liver compared to the results of a liver biopsy.
People 18 years of age and older who are scheduled to have or who have already had a liver biopsy as part of their medical care within 1 month of enrollment in this study may be eligible to participate.
Participants undergo an MRI. For this procedure, the subject lies still on a table that slides into a narrow metal cylinder (the MRI scanner) for 30 to 60 minutes. A special pad or tube is placed around the abdomen to improve the image of the liver obtained. Earplugs are placed in the ears to muffle loud thumping and knocking sounds that occur with the electrical switching of the magnetic field. The findings of the MRI are compared with those of the liver biopsy.
|Condition or disease||Intervention/treatment||Phase|
|Fatty Liver Hepatitis||Procedure: Diagnostic Radiology: 1H-MRS of the liver||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||53 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||Validation of (1)H-Magnetic Resonance Spectroscopy for Quantification of Hepatic Triglyceride Content|
|Study Start Date :||December 20, 2007|
|Actual Primary Completion Date :||July 1, 2010|
|Actual Study Completion Date :||June 15, 2011|
- Validate 1H-Magnetic Resonance Spectroscopy to assess hepatic steatosis
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00594412
|United States, Maryland|
|National Institutes of Health Clinical Center, 9000 Rockville Pike|
|Bethesda, Maryland, United States, 20892|