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Brain Tissue Specimen Collection

This study is enrolling participants by invitation only.
Information provided by (Responsible Party):
Reid Thompson, Vanderbilt University Medical Center Identifier:
First received: January 2, 2008
Last updated: March 30, 2017
Last verified: March 2017
The Molecular Neurosurgical Tissue Bank will function as a tissue or specimen repository for biopsy specimens from patients (both adult and pediatric) undergoing brain surgery and brain procedures. Leftover tissue removed during the course of brain surgery will be collected and stored in neurosurgical laboratories for use in medical research that might be currently ongoing or for future research. In addition, blood and cerebral spinal fluid samples will also be collected and stored. Leftover cerebral spinal fluid (CSF) will be collected during standard of care procedures (lumbar punctures or ventricular drains) that take place at time of diagnosis, completion of therapy and relapse of disease or during neurosurgery. Blood will be drawn at time of routine lab draws required during the surgery or procedure.

Brain Diseases

Study Type: Observational
Study Design: Observational Model: Other
Time Perspective: Prospective
Official Title: Molecular Neurosurgical Tissue Bank

Resource links provided by NLM:

Further study details as provided by Reid Thompson, Vanderbilt University Medical Center:

Biospecimen Retention:   Samples With DNA
Brain Tissue, blood and cerebral spinal fluid

Estimated Enrollment: 500
Study Start Date: May 2003
Estimated Study Completion Date: December 2017
Estimated Primary Completion Date: December 2017 (Final data collection date for primary outcome measure)

Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
infant through Adults

Inclusion Criteria:

  • Subjects having any type of brain surgery, where a specimen will be collected.

Exclusion Criteria:

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00593203

United States, Tennessee
Vanderbilt University Medical Center, Deptartment of Neurological Surgery
Nashville, Tennessee, United States, 37232
Sponsors and Collaborators
Vanderbilt University Medical Center
Principal Investigator: Reid C. Thompson, M.D. Vanderbilt University Medical Center, Department of Neurological Surgery
  More Information

Responsible Party: Reid Thompson, Director, Vanderbilt University Medical Center Identifier: NCT00593203     History of Changes
Other Study ID Numbers: 030372
Study First Received: January 2, 2008
Last Updated: March 30, 2017
Individual Participant Data  
Plan to Share IPD: No

Additional relevant MeSH terms:
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases processed this record on June 22, 2017