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Effects of Medical and Surgical Weight Loss on Metabolism (BOS)

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ClinicalTrials.gov Identifier: NCT00592735
Recruitment Status : Completed
First Posted : January 14, 2008
Last Update Posted : June 7, 2016
Sponsor:
Information provided by (Responsible Party):

Study Description
Brief Summary:
This study will follow ,morbidly obese subjects as they undertake weight loss before and after laparoscopic gastric banding, examining markers of glucose and lipid metabolism, adipokines and measures of body fat.

Condition or disease Intervention/treatment
Type 2 Diabetes Obesity Procedure: laparoscopic gastric banding

Study Design

Study Type : Observational
Actual Enrollment : 20 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: The Role of Adipocyte-derived Inflammatory Cytokines in the Pathogenesis of Diabetes, Dyslipidaemia, Atherosclerosis and Gastro-oesophageal Reflux Disease: the Effects of Medical and Surgical Weight Loss
Study Start Date : May 2007
Primary Completion Date : May 2012
Study Completion Date : May 2012

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Groups and Cohorts

Group/Cohort Intervention/treatment
1 Procedure: laparoscopic gastric banding
standard surgical procedure


Outcome Measures

Primary Outcome Measures :
  1. weight loss [ Time Frame: 6 months ]

Biospecimen Retention:   Samples With DNA
serum, tissue

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 70 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
morbidly obese subjects with type 2 diabetes or metabolic syndrome
Criteria

Inclusion Criteria:

  • morbidly obese subjects with type 2 diabetes or metabolic syndrome
  • age <70

Exclusion Criteria:

  • contra-indications to bariatric surgery
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00592735


Locations
Australia, New South Wales
St Vincent's Hospital
Sydney, New South Wales, Australia, 2010
Sponsors and Collaborators
Garvan Institute of Medical Research
More Information

Responsible Party: Professor Katherine Samaras, Garvan Institute of Medical Research
ClinicalTrials.gov Identifier: NCT00592735     History of Changes
Other Study ID Numbers: SVH H06/151
First Posted: January 14, 2008    Key Record Dates
Last Update Posted: June 7, 2016
Last Verified: June 2016

Additional relevant MeSH terms:
Weight Loss
Body Weight Changes
Body Weight
Signs and Symptoms