Menstrual Cycle Maintenance and Quality of Life: A Prospective Study
Very little is known about the incidence, onset, time course, and symptomatology of premature menopause induced by breast cancer therapy. No prospective study exists. The purpose of the present study is to identify determinants of treatment-related amenorrhea nad its effect on quality of life in a cohort of youg breast cancer patients.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Menstrual Cycle Maintenance and Quality of Life: A Prospective Study|
- The overall goal of the proposed research is to recruit and follow young breast cancer patients aged 45 and younger, in order to examine menstrual cycle maintenance. [ Time Frame: Conclusion of the study ] [ Designated as safety issue: No ]
- Examine possible predictors of treatment-related amenorrhea including age, smoking history, race, and treatment variables [ Time Frame: Conclusion of study ] [ Designated as safety issue: No ]
|Study Start Date:||December 1997|
|Estimated Study Completion Date:||December 2015|
|Estimated Primary Completion Date:||December 2015 (Final data collection date for primary outcome measure)|
Data collection instruments will be obtained at baseline and every six months. Follow-up will range between 26-42 months for participants.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00589654
|United States, New York|
|Memorial Sloan Kettering Cancer Center|
|New York, New York, United States, 10065|
|Principal Investigator:||Kimberly Van Zee, MD||Memorial Sloan Kettering Cancer Center|