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Age Related Changes in Calciotropic Hormones and Their Impact on Male Osteoporosis

This study is ongoing, but not recruiting participants.
National Institute on Aging (NIA)
Information provided by:
Yale University Identifier:
First received: December 27, 2007
Last updated: January 8, 2008
Last verified: December 2007
The purpose of this pilot study is to generate preliminary data regarding the skeletal effects of age-related changes in calcium and vitamin D metabolism in older men.

Low Bone Density

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Cross-Sectional
Official Title: Pilot Study to Assess the Skeletal Effects of Age-Related Changes in Calcium and Vitamin D Metabolism in Men

Resource links provided by NLM:

Further study details as provided by Yale University:

Primary Outcome Measures:
  • Bone density of hip and spine [ Time Frame: measured after screening evaluation ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • calciotropic hormones, including calcium, PTH and vitamin D metabolites [ Time Frame: measured after screening evaluation ] [ Designated as safety issue: No ]

Enrollment: 24
Study Start Date: October 2000
Estimated Study Completion Date: December 2008
Primary Completion Date: July 2002 (Final data collection date for primary outcome measure)
men 50 yrs of age or older


Ages Eligible for Study:   50 Years and older   (Adult, Senior)
Genders Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Healthy men 50 yrs of age and older, without a known history of metabolic bone disease or renal insufficiency

Inclusion Criteria:

  • healthy men age 50 yrs and older

Exclusion Criteria:

  • smokers
  • known history of metabolic bone disease, known history of hypogonadism or renal insufficiency.
  Contacts and Locations
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Please refer to this study by its identifier: NCT00588874

United States, Connecticut
Yale Center for Clinical Investigation
New Haven, Connecticut, United States, 06520
Sponsors and Collaborators
Yale University
National Institute on Aging (NIA)
Principal Investigator: Barbara I Gulanski, MD, MPH Yale University
  More Information

Responsible Party: Barbara I. Gulanski, MD, MPH, Yale University School of Medicine Identifier: NCT00588874     History of Changes
Other Study ID Numbers: 11946  Pepper Center Pilot Award 
Study First Received: December 27, 2007
Last Updated: January 8, 2008
Health Authority: United States: Institutional Review Board

Keywords provided by Yale University:
male osteoporosis
male osteopenia
calciotropic hormones

Additional relevant MeSH terms:
Bone Diseases, Metabolic
Bone Diseases
Musculoskeletal Diseases processed this record on January 14, 2017