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Ramanspectroscopy in Barrett's Esophagus

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00588575
First Posted: January 8, 2008
Last Update Posted: January 7, 2016
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Collaborator:
National Institutes of Health (NIH)
Information provided by (Responsible Party):
Louis-Michel Wong Kee Song, Mayo Clinic
  Purpose
This study is being done to see if a new device, called near-infrared Raman spectroscopy, can provide similar information as that obtained from taking biopsies of the lining of your Barrett's esophagus

Condition
Barrett's Esophagus

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: In-Vivo Raman Spectroscopy of Barrett's Esophagus

Further study details as provided by Louis-Michel Wong Kee Song, Mayo Clinic:

Biospecimen Retention:   Samples Without DNA
esophageal biopsy

Enrollment: 119
Study Start Date: October 2004
Study Completion Date: October 2007
Primary Completion Date: May 2007 (Final data collection date for primary outcome measure)
Detailed Description:
In the search for means to enhance the surveillance of BE, optical spectroscopy is emerging as a candidate with high potential. Optical spectroscopic techniques measure specific light-tissue interactions, such as fluorescence, elastic scattering, and Raman (inelastic) scattering, which provide objective and quantitative diagnostic information about the molecular and/or structural status of tissue. Moreover, optical spectroscopy has the capacity to identify tissue pathology in situ in a rapid and non-destructive fashion. Among the optical spectroscopic techniques, near-infrared Raman spectroscopy (NIRS) is particularly promising because of the wealth of molecular-specific information contained in its spectra
  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years to 85 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Barrett's esophagus surveillance
Criteria

Inclusion Criteria:

  • Closed to further enrollment
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00588575


Locations
United States, Minnesota
Mayo Clinic
Rochester, Minnesota, United States, 55905
Sponsors and Collaborators
Mayo Clinic
National Institutes of Health (NIH)
Investigators
Principal Investigator: Louis M Wongkeesong, MD Mayo Clinic
  More Information

Additional Information:
Responsible Party: Louis-Michel Wong Kee Song, Principal Investigator, Mayo Clinic
ClinicalTrials.gov Identifier: NCT00588575     History of Changes
Other Study ID Numbers: 1999-04 00
DK67148
Raman
First Submitted: December 22, 2007
First Posted: January 8, 2008
Last Update Posted: January 7, 2016
Last Verified: September 2009

Keywords provided by Louis-Michel Wong Kee Song, Mayo Clinic:
Barrett's Esophagus

Additional relevant MeSH terms:
Barrett Esophagus
Digestive System Abnormalities
Digestive System Diseases
Esophageal Diseases
Gastrointestinal Diseases