Efficacy of Social Cognition Training in Schizophrenia

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00587561
Recruitment Status : Active, not recruiting
First Posted : January 7, 2008
Last Update Posted : May 2, 2018
Information provided by (Responsible Party):
VA Connecticut Healthcare System

Brief Summary:

The term social cognition refers to how social information is processed. Individuals with schizophrenia and schizoaffective disorder have been shown to have significant deficits in social cognition. Moreover, it has been speculated that these deficits may in turn have a negative impact on their overall functioning. Behavioral interventions targeting social cognition are just beginning to emerge, and there is a need to evaluate their efficacy.


This is a small trial evaluating the efficacy of social cognition interaction training (SCIT) an experimental behavioral treatment for improving social cognition in schizophrenia.

Research Design and Methodology:

Approximately 48 participants with schizophrenia-spectrum disorders will be randomized into one of two conditions: 1) a 20 to 24 session manualized social cognition interaction training group (SCIT), or 2) wait-list control. Pre-and post-group therapy assessments of symptoms, social cognition, basic cognition, and community function will be conducted. Data obtained from this study will allow us to determine the efficacy of SCIT training in improving symptom, cognitive, and functional measures.

Condition or disease Intervention/treatment Phase
Schizophrenia Behavioral: Social Cognition Interaction Training Behavioral: WLC Not Applicable

Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 75 participants
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Efficacy of Social Cognition Training in Schizophrenia
Study Start Date : January 2008
Actual Primary Completion Date : December 2013
Estimated Study Completion Date : December 2019

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Schizophrenia

Arm Intervention/treatment
Experimental: 1
Will receive 20-26 sessions of a manualized group treatment called Social Cognition Interaction Training
Behavioral: Social Cognition Interaction Training
manualized group therapy

Wait list control; 6 months of treatment as usual followed by Social Cognition Interaction Training group
Behavioral: WLC
wait-list control for 6 months, followed by the experimental group therapy

Primary Outcome Measures :
  1. Social cognitive measures [ Time Frame: intake, 6 months, 9 months ]

Secondary Outcome Measures :
  1. basic cognitive measures [ Time Frame: intake, 6 months, 9 months ]

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 65 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • diagnosis of schizophrenia or schizoaffective disorder
  • Age between 18 and 65
  • minimum of 30 days since discharge from last hospitalization
  • minimum of 30 days since last change in psychiatric medications
  • no housing changes in the past 30 days

Exclusion Criteria:

  • current diagnosis of alcohol or substance abuse/dependence
  • history of brain trauma or neurological disease
  • mental retardation or developmental disability
  • auditory or visual impairment that would interfere with study procedures

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00587561

United States, Connecticut
Connecticut Mental Health Center
New Haven, Connecticut, United States, 06510
VA Connecticut Healthcare System
West Haven, Connecticut, United States, 06516
Sponsors and Collaborators
VA Connecticut Healthcare System
Principal Investigator: Joanna Fiszdon, Ph.D. VA Connecticut Heathcare System and Yale University

Responsible Party: VA Connecticut Healthcare System Identifier: NCT00587561     History of Changes
Other Study ID Numbers: JMF0005
First Posted: January 7, 2008    Key Record Dates
Last Update Posted: May 2, 2018
Last Verified: May 2018

Keywords provided by VA Connecticut Healthcare System:
social cognition

Additional relevant MeSH terms:
Schizophrenia Spectrum and Other Psychotic Disorders
Mental Disorders