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Wisconsin Brain Donor Program (WBDP)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00585572
Recruitment Status : Enrolling by invitation
First Posted : January 3, 2008
Last Update Posted : December 2, 2019
University of Washington
Information provided by (Responsible Party):
University of Wisconsin, Madison

Brief Summary:
The Wisconsin Brain Donor Program (WBDP) stores brain and other tissues/samples (e.g. blood and CSF) from deceased individuals who have participated in longitudinal research studies, as well as other select participants. These individuals have donated their tissues in order to aid scientific research. Through the collection of central and peripheral nervous tissues as well as (in select cases) skeletal muscle tissue, the WBDP strives to advance the knowledge of diseases of memory disorders, such as Alzheimer's Disease. Brain donations are needed from healthy individuals, as well as those affected by diseases of the nervous system.

Condition or disease
Alzheimer's Disease Mild Cognitive Impairment

Detailed Description:
The WBDP strives to provide well-characterized tissues/samples to researchers. The WBDP is aligned with the longitudinal research study of the Alzheimer's Disease Research Center (ADRC) in Madison, Wisconsin as well as other studies associated with the ADRC.

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Study Type : Observational
Estimated Enrollment : 500 participants
Observational Model: Other
Time Perspective: Other
Official Title: University of Wisconsin-Madison: Wisconsin Brain Donor Program (WBDP)
Study Start Date : March 2007
Estimated Primary Completion Date : October 2020
Estimated Study Completion Date : October 2020

Biospecimen Retention:   Samples Without DNA
Brain tissue, blood, cerebrospinal fluid, spinal cord, peripheral nerves, and skeletal muscles, central/peripheral nervous tissue, as well as skeletal muscle tissue.

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Participants agree to autopsy and brain/tissue/sample donation for research purposes only.
Individuals enrolled in the longitudinal study of the Alzheimer's Disease Research Center (ADRC), additional studies affiliated with the ADRC, or select additional donors are invited to participate.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00585572

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United States, Wisconsin
University of Wisconsin Madison
Madison, Wisconsin, United States, 53792
Sponsors and Collaborators
University of Wisconsin, Madison
University of Washington
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Principal Investigator: Shahriar Salamat, MD PHD University of Wisconsin, Madison

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Responsible Party: University of Wisconsin, Madison Identifier: NCT00585572    
Other Study ID Numbers: H-2010-0037
H-2010-0037 ( Other Identifier: IRB )
H-2014-1484 ( Other Identifier: IRB )
A534255 ( Other Identifier: University of Wisconsin, Madison )
GERIATRICS AND ADULT ( Other Identifier: UW, Madison )
First Posted: January 3, 2008    Key Record Dates
Last Update Posted: December 2, 2019
Last Verified: November 2019
Keywords provided by University of Wisconsin, Madison:
Normal Tissues/Brains
Motor Neuron Disease
Healthy Control Volunteers
Populations At Risk
Additional relevant MeSH terms:
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Alzheimer Disease
Cognitive Dysfunction
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Neurodegenerative Diseases
Neurocognitive Disorders
Mental Disorders
Cognition Disorders