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Corneal Topographer Fluorescein Patterns

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ClinicalTrials.gov Identifier: NCT00584285
Recruitment Status : Completed
First Posted : January 2, 2008
Results First Posted : November 2, 2018
Last Update Posted : November 2, 2018
Sponsor:
Information provided by (Responsible Party):
Christine Sindt, University of Iowa

Brief Summary:
The objective of this study is to determine if corneal topography can be used to predict the fluorescein pattern of keratoconus lenses on the eye. A corneal topography image will be taken and the computer selected lens will be placed on the eye. After placement of the lens color photographs will be taken of the eye's fluorescein pattern and compared to the computer predicted pattern.

Condition or disease
Keratoconus

Detailed Description:

Subject population: keratoconus patients who have not undergone corneal surgery 100 subjects who come to UIHC for their contact lens care. We will approach them at their visit. We will not call potential participants from a database.

If topography is impossible to capture. Concommitant Corneal Disease Minors will be excluded


Study Type : Observational
Actual Enrollment : 18 participants
Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Objective and Subjective Correlation Between Clinical Fluorescein Patterns and Theoretical Patterns Using the Medmont Corneal Topographer
Actual Study Start Date : September 15, 2007
Actual Primary Completion Date : September 4, 2009
Actual Study Completion Date : September 14, 2009

Resource links provided by the National Library of Medicine


Group/Cohort
Corneal Topographer Fluorescein Patterns
Use corneal topography to evaluate fluorescein pattern of rgp contact lens. Used corneal topography to develop theoretical fluorescein patters on a virtual eye. Theoretical lens developed by the topographer was ordered to compare to the actual fluorescein pattern on the actual eye.



Primary Outcome Measures :
  1. Number of Participants With an Observable Difference Between Virtual Versus Actual Fluorescein Patterns [ Time Frame: Baseline first visit ]
    Comparison of fluorescein patterns of rgp contact lens. Bearing and elevation fluorescein patterns will be compared between the actual (photo) and theoretical (computer generated) fluorescein patterns using standard clinical means.



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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
18 yrs of age or older with diagnosis of keratoconus and contact lens wearer
Criteria

Inclusion Criteria:

18 yrs of age or older with diagnosis of keratoconus and contact lens wearer

Exclusion Criteria:

Noncommittant corneal disease or surgery Inability to capture topography measurement


Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00584285


Locations
United States, Iowa
University of Iowa Hospitals and Clinics - Dept. of Ophthalmology
Iowa City, Iowa, United States, 52242
Sponsors and Collaborators
Christine Sindt
Investigators
Principal Investigator: Christine W. Sindt, OD University of Iowa

Publications:
Responsible Party: Christine Sindt, Asscociate Professor, University of Iowa
ClinicalTrials.gov Identifier: NCT00584285     History of Changes
Other Study ID Numbers: 200709737
First Posted: January 2, 2008    Key Record Dates
Results First Posted: November 2, 2018
Last Update Posted: November 2, 2018
Last Verified: March 2018
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Product Manufactured in and Exported from the U.S.: No

Additional relevant MeSH terms:
Keratoconus
Corneal Diseases
Eye Diseases