Corneal Topographer Fluorescein Patterns

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00584285
Recruitment Status : Unknown
Verified December 2007 by University of Iowa.
Recruitment status was:  Recruiting
First Posted : January 2, 2008
Last Update Posted : January 2, 2008
Information provided by:
University of Iowa

Brief Summary:
The objective of this study is to determine if corneal topography can be used to predict the fluorescein pattern of keratoconus lenses on the eye. A corneal topography image will be taken and the computer selected lens will be placed on the eye. After placement of the lens color photographs will be taken of the eye's fluorescein pattern and compared to the computer predicted pattern.

Condition or disease Intervention/treatment Phase
Keratoconus Other: Comparison of fluorescein patterns Not Applicable

Detailed Description:

Subject population: keratoconus patients who have not undergone corneal surgery 100 subjects who come to UIHC for their contact lens care. We will approach them at their visit. We will not call potential participants from a database.

If topography is impossible to capture. Concommitant Corneal Disease Minors will be excluded

Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 0 participants
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Supportive Care
Official Title: Objective and Subjective Correlation Between Clinical Fluoroscein Patterns and Theoretical Patterns Using the Medmont Corneal Topographer
Study Start Date : November 2007
Estimated Primary Completion Date : December 2010

Resource links provided by the National Library of Medicine

Arm Intervention/treatment
Active Comparator: 1 Other: Comparison of fluorescein patterns
Compare conventional contact lens fitting to fitting contact lenses based on corneal topography measurement

Primary Outcome Measures :
  1. There will be no inter-patient comparison. Bearing and elevation fluorescein patterns will be compared between the actual (photo) and theoretical (computer generated) fluorescein patterns. [ Time Frame: 1 year after last subject is enrolled ]

Secondary Outcome Measures :
  1. Improved comfort [ Time Frame: one day ]

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

18yrs of age or older diagnosis of keratoconus contact lens wearer

Exclusion Criteria:

Concommittant corneal disease or surgery Inability to capture topography measurement

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00584285

Contact: Christine W Sindt, OD 319-356-4816

United States, Iowa
University of Iowa Hospitals and Clinics - Dept. of Ophthalmology Recruiting
Iowa City, Iowa, United States, 52242
Principal Investigator: Christine W Sindt, OD         
Sponsors and Collaborators
University of Iowa
Principal Investigator: Christine W. Sindt, OD University of Iowa

Responsible Party: Christine Sindt, OD, University of Iowa Identifier: NCT00584285     History of Changes
Other Study ID Numbers: 200709737
First Posted: January 2, 2008    Key Record Dates
Last Update Posted: January 2, 2008
Last Verified: December 2007

Additional relevant MeSH terms:
Corneal Diseases
Eye Diseases