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Improving Walking in Older Adults With Knee Osteoarthritis

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00583245
First Posted: December 31, 2007
Last Update Posted: March 10, 2017
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Collaborator:
National Institute on Aging (NIA)
Information provided by (Responsible Party):
Neil A Segal, University of Iowa
  Purpose
Knee osteoarthritis (OA) accounts for a significant proportion of mobility limitations and is one of the most disabling problems facing the growing population of older adults. The long-term objective of this research is to reduce disablement of older adults with symptomatic knee OA. The principle of specificity of training indicates that exercises that closely approximate the goal functional activity are most effective in improving physical performance during that activity. Based on this principle, the specific aim of this pilot study is to design a patient-specific gait training intervention using analysis of compensatory joint moments and energy expenditure. Successful completion will inform rehabilitation for maintaining or improving mobility as well as explore the mechanism of effect.

Condition Intervention
Knee Osteoarthritis Other: Gait Training

Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Optimizing Mobility in Older Adults With Knee Osteoarthritis

Resource links provided by NLM:


Further study details as provided by Neil A Segal, University of Iowa:

Primary Outcome Measures:
  • Changes in functional limitation assessed by the A) Summary Performance Score which includes balance tests, timed 4-meter walk, and timed chair stand test B) Timed stair climb C) Late Life Function and Disability Instrument (LLFDI) Questionnaire [ Time Frame: 12 weeks ]
  • Changes in the disability measure, a timed 400 meter walk [ Time Frame: 12 Weeks ]
  • Changes in impairments assessed using the Knee and Osteoarthritis Outcome Score (KOOS) questionnaire [ Time Frame: 12 Weeks ]

Enrollment: 27
Study Start Date: December 2007
Study Completion Date: December 2009
Primary Completion Date: September 2008 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: 1
Gait training
Other: Gait Training
Gait training with physical therapist 2/week for 3 months

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   60 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Symptomatic knee osteoarthritis (knee osteoarthritis diagnosed by x-ray and frequent knee symptoms)
  • Age 60 or older

Exclusion Criteria:

  • acute or terminal illness
  • unstable cardiovascular condition or other medical conditions that may impair ability to participate such as pulmonary disease requiring the use of supplemental oxygen, neurological disease that affects gait, or lower limb musculoskeletal surgery in the past 6 months.
  • Bilateral knee replacement
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00583245


Locations
United States, Iowa
University of Iowa
Iowa City, Iowa, United States, 52242
Sponsors and Collaborators
University of Iowa
National Institute on Aging (NIA)
Investigators
Principal Investigator: Neil Segal, MD University of Iowa
  More Information

Responsible Party: Neil A Segal, Professor, University of Iowa
ClinicalTrials.gov Identifier: NCT00583245     History of Changes
Other Study ID Numbers: 200704794
1K23AG030945-01 ( U.S. NIH Grant/Contract )
First Submitted: December 20, 2007
First Posted: December 31, 2007
Last Update Posted: March 10, 2017
Last Verified: March 2017

Keywords provided by Neil A Segal, University of Iowa:
Osteoarthritis
Gait training
Knee pain
Rehabilitation
Physical Therapy

Additional relevant MeSH terms:
Osteoarthritis
Osteoarthritis, Knee
Arthritis
Joint Diseases
Musculoskeletal Diseases
Rheumatic Diseases


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