Long-Term Outcome of Children and Adolescents With Anti-Phospholipid Antibodies (APL)
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|ClinicalTrials.gov Identifier: NCT00581763|
Recruitment Status : Completed
First Posted : December 28, 2007
Last Update Posted : June 13, 2012
|Condition or disease|
- Determine the incidence, and time frame, for aquiring aPL in a cohort of aPL-negative pediatric SLE subjects.
- Determine the incidence, and time frame, for developing a first APS-associated complication among SLE subjects with detectable aPL.
- Determine the incidence, and time frame, for developing a second APS-associated event among subjects with a history of an APS-associated event.
- Determine the incidence, and time frame, for developing SLE among subjects with a history of an APS-associated event in the absence of SLE.
- Identify laboratory and clinical predictors for the events described in aims 1-4.Research Design and Methods:
This is a prospective cohort study to determine the risk of developing aPL or APS-related symptoms in a young group of SLE and APS subjects. Patients will be followed over a ten year period and will undergo annual serologic and clinical evaluations to identify disease progression.
|Study Type :||Observational|
|Actual Enrollment :||110 participants|
|Official Title:||Long-Term Outcome of Children and Adolescents With Anti-Phospholipid Antibodies|
|Study Start Date :||May 2001|
|Actual Study Completion Date :||June 2011|
Those with a condition
- Evaluate changes and improve ability to determine the long-term outcome of affected individuals [ Time Frame: Ten years ]
Biospecimen Retention: Samples With DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00581763
|United States, California|
|University of California, San Francisco|
|San Francisco, California, United States, 94143|
|Principal Investigator:||Emily von Scheven||University of California, San Francisco|