Action of Caffeinated and Decaffeinated Espresso on Autonomic Function
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|ClinicalTrials.gov Identifier: NCT00576030|
Recruitment Status : Terminated
First Posted : December 18, 2007
Last Update Posted : July 5, 2010
More than 80% of the population in the USA consume coffee each day. However there not many studies on change of heart rate variability and placebo effects after consumption of coffee.
In our study we aim to test the following hypotheses:
- Habitual caffeinated espresso coffee drinkers show an increase in blood pressure, heart rate variability and parasympathetic activity (high frequency band) of the heart.
- Non-habitual caffeinated espresso coffee drinkers show an increase of blood pressure. The heart rate variability and the parasympathetic activity of the heart will decrease.
- Caffeinated or decaffeinated espresso induces comparable changes in habitual or non-habitual coffee drinkers.
|Condition or disease||Intervention/treatment||Phase|
|Influence of Espresso on Heart Rate Variability||Other: hab cof with water Other: hab cof with dec espresso Other: hab cof with caf espresso Other: non-hab cof with water Other: non-hab cof with dec espresso Other: non-hab cof with caf espresso||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||77 participants|
|Intervention Model:||Crossover Assignment|
|Masking:||Triple (Participant, Care Provider, Investigator)|
|Primary Purpose:||Basic Science|
|Official Title:||Short-term Autonomic Effects of Caffeinated and Decaffeinated Espresso in Young Healthy Individuals|
|Study Start Date :||January 2007|
|Actual Primary Completion Date :||October 2008|
|Actual Study Completion Date :||October 2008|
habitual coffee drinkers
Other: hab cof with water
habitual coffee drinker provided with waterOther: hab cof with dec espresso
habitual coffee drinkers given decaffeinated espressoOther: hab cof with caf espresso
habitual coffee drinkers given caffeinated espresso
non-habitual coffee drinkers
Other: non-hab cof with water
non-habitual coffee drinkers given waterOther: non-hab cof with dec espresso
non-habitual coffee drinkers given decaffeinated espressoOther: non-hab cof with caf espresso
non-habitual coffee drinkers given caffeinated espresso
- Heart rate variability [ Time Frame: 70 minutes ]
- blood pressure [ Time Frame: 70 min. ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00576030
|Department of Psychosomatic Medicine and Psychotherapy, Charité University|