Prospective Analysis and Comparison of Stress Echo to Real-Time Myocardial Contrast Stress Echo
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The purpose of this study is to prospectively analyze and compare conventional stress echocardiograms and real-time myocardial contrast stress echocardiograms; and to determine the effect of contrast agents used during real-time myocardial contrast stress echocardiograms on serum troponin I levels.
Condition or disease
Evaluation of Troponin I Levels
Other: Dobutamine: Perflutren Lipid Microsphere
To compare two different stress echocardiograms (conventional Stress echocardiograms or Real-time Myocardial Contrast Stress Echocardiograms) that are in routine clinical use. The information, including the digital images that are collected during the stress tests is used to determine if the usse of specialized imaging techniques and ultrasound contrast can better detect blockage in blood flow to the heart and predict how patients outcome may be affected by this detection of a blockage.
Prospective Analysis and Comparison of Conventional Stress Echocardiograms and Real-Time Myocardial Contrast Stress Echocardiogram; for Bristol-Myers Squibb Medical Imaging: The Definity RT-P During DSE Database
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Layout table for eligibility information
Ages Eligible for Study:
19 Years and older (Adult, Older Adult)
Sexes Eligible for Study:
Male or female
Age > 19 years
Scheduled for a stress echocardiography
Are conscious and coherent, and able to communicate effectively with trial personnel
For troponin evaluation, only hospitalized patients who had a troponin level drawn in the morning of and prior to stress echocardiogram will be included.
Pregnant and breast feeding women are excluded from participation because of the possibility of a bias as CSE is routinely used in pregnant patients secondary to lack of human studies to determine the fetal risk of use of Definity.
Age < 19 years old
Known or suspected hypersensitivity to ultrasound contrast agents or other drugs used for the study
Possibility that potential subject may be pregnant
Studies where RT-MCE was specifically requested by the ordering physician