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Prediction of Thyroid Cancer From Ultrasonographic Characteristics of Thyroid Nodules

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ClinicalTrials.gov Identifier: NCT00571090
Recruitment Status : Completed
First Posted : December 11, 2007
Last Update Posted : March 31, 2014
Sponsor:
Collaborator:
Group Florence Nightingale
Information provided by (Responsible Party):
Ahmet Selcuk Can, Istanbul Science University

Brief Summary:
The aim of this study is to identify which ultrasonographic feature or a combination of features is the best predictor of thyroid cancer in thyroid nodules.

Condition or disease Intervention/treatment
Thyroid Nodule Procedure: Thyroid ultrasonography

Study Type : Observational
Actual Enrollment : 735 participants
Observational Model: Case-Only
Time Perspective: Cross-Sectional
Official Title: Evaluation of Thyroid Fine Needle Aspiration Biopsies: Prediction of Thyroid Cancer From Ultrasonographic Characteristics of Thyroid Nodules
Study Start Date : June 2003
Actual Primary Completion Date : July 2012
Actual Study Completion Date : July 2013

Resource links provided by the National Library of Medicine

Drug Information available for: Thyroid
U.S. FDA Resources

Group/Cohort Intervention/treatment
Thyroid nodule
Subjects who present with thyroid nodules will be enrolled into the study. Euthyroid and hypothyroid subjects with a solitary thyroid nodule or multinodular goiter will be enrolled. For subjects with a suppressed TSH, a thyroid scan will be performed. Subjects with a hypoactive nodule in the thyroid scan and a low TSH will be enrolled.
Procedure: Thyroid ultrasonography
Ultrasound-guided thyroid fine-needle aspiration biopsy



Primary Outcome Measures :
  1. Thyroid cancer [ Time Frame: one year ]


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Ages Eligible for Study:   15 Years to 89 Years   (Child, Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Endocrinology Clinic
Criteria

Inclusion Criteria:

  • Subjects with thyroid nodules over 10 mm in the longest diameter
  • Euthyroid or hypothyroid subjects with a solitary thyroid nodule or multinodular goiter
  • Subjects with a hypoactive nodule in the thyroid scan and a low TSH

Exclusion Criteria:

  • Subjects with four or more thyroid nodules that are over 10 mm
  • Subjects with low TSH and hyperactive nodule on thyroid scan

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00571090


Locations
Turkey
Group Florence Nightingale
Istanbul, Turkey
Sponsors and Collaborators
Istanbul Science University
Group Florence Nightingale
Investigators
Principal Investigator: Ahmet Selcuk Can, MD Istanbul Science University and Group Florence Nightingale

Additional Information:
Publications:
Responsible Party: Ahmet Selcuk Can, Associate Professor of Medicine, Istanbul Science University
ClinicalTrials.gov Identifier: NCT00571090     History of Changes
Other Study ID Numbers: B.30.2.IBU.0.01.00.00/511
511 ( Other Identifier: Istanbul Science University )
First Posted: December 11, 2007    Key Record Dates
Last Update Posted: March 31, 2014
Last Verified: March 2014

Keywords provided by Ahmet Selcuk Can, Istanbul Science University:
Thyroid nodule
Biopsy, Fine-Needle

Additional relevant MeSH terms:
Thyroid Diseases
Thyroid Neoplasms
Thyroid Nodule
Endocrine System Diseases
Endocrine Gland Neoplasms
Neoplasms by Site
Neoplasms
Head and Neck Neoplasms