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Agreement Between Venous and Arterial Blood Gas Measurements in the Intensive Care Unit (AVANTI)

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ClinicalTrials.gov Identifier: NCT00569634
Recruitment Status : Completed
First Posted : December 7, 2007
Last Update Posted : August 29, 2016
Sponsor:
Collaborator:
Olive View-UCLA Education & Research Institute
Information provided by (Responsible Party):
University of California, Los Angeles

Brief Summary:
The purpose of this study is to examine the agreement between venous blood gas and arterial blood gas measurements in patients in the Intensive Care Unit.

Condition or disease Intervention/treatment Phase
Acid-Base Balance Procedure: Venous blood gas analysis Not Applicable

Detailed Description:
Venous blood gas analysis may be an alternative to arterial blood gas analysis for acid-base status, reducing the need for frequent invasive arterial sampling. The objective of this study is to examine the agreement between ABG and VBG samples for all commonly used parameters (pH, pCO2 and bicarbonate) in a pathologically diverse ICU patient population, specifically analyzing multiple paired arterial and venous samples from each patient.

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 40 participants
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Diagnostic
Official Title: Agreement Between Venous and Arterial Blood Gas Measurements in the Intensive Care Unit
Study Start Date : January 2008
Actual Primary Completion Date : July 2008
Actual Study Completion Date : July 2008

Arm Intervention/treatment
1 Procedure: Venous blood gas analysis
When an ABG is deemed to be necessary as part of ICU management, a central venous sample will also be obtained with minimum delay (always < 2 minutes) between the samples. The samples will be analyzed by a blood gas analyzer as quickly as possible.



Primary Outcome Measures :
  1. Agreement between venous and arterial blood gas measurements of pH, pCO2 and bicarbonate [ Time Frame: Duration of Intensive Care Unit Admission ]


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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Adult patients 18 years or older
  • Admitted to the Intensive Care Unit (ICU)
  • Determined by their treating clinicians to require both a central venous line and arterial line

Exclusion Criteria:


Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00569634


Sponsors and Collaborators
University of California, Los Angeles
Olive View-UCLA Education & Research Institute
Investigators
Principal Investigator: Richard M Treger, M.D. Olive View-UCLA Education & Research Institute

Publications:

Responsible Party: University of California, Los Angeles
ClinicalTrials.gov Identifier: NCT00569634     History of Changes
Other Study ID Numbers: 07H-821001
First Posted: December 7, 2007    Key Record Dates
Last Update Posted: August 29, 2016
Last Verified: August 2016

Keywords provided by University of California, Los Angeles:
Venous blood gas
Arterial blood gas
pH
pCO2
Bicarbonate