Study of the Pathogenesis and Molecular Mechanism of "YURE" in Internal Intractable Diseases
Recruitment status was: Recruiting
|Study Design:||Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Outcomes Assessor)
Primary Purpose: Treatment
|Official Title:||"973" Project for Pathology of Traditional Chinese Medicine|
- Chinese symptoms [ Time Frame: 21 days ] [ Designated as safety issue: No ]
- blood loss determined by brain CT [ Time Frame: 21 days ] [ Designated as safety issue: No ]
|Study Start Date:||November 2007|
|Estimated Study Completion Date:||December 2010|
|Estimated Primary Completion Date:||April 2010 (Final data collection date for primary outcome measure)|
A combined treatment would be used in the arm.That means Chinese herb formula would be used with the current Modern Medicine therapy for stroke in this arm.
Drug: Chinese herbs formula
The chinese herbs formula includes eight herbs,and they are Radix et Rhizoma Rhei Palmati(Rhubarb,10 grams),Cornu Bubali(Buffalo Horn,30 grams),Radix Paeoniae Bubra(Red Peony Root,15 grams),Cortex Moutan Radicis(Tree Peony Root-bark,10 grams),Radix Rehmanniae(Adhesive Rehmannia Root Tuber,20 grams),Pheretima Aspergillum(Earth-worm,10 grams),Radix Notoginseng(Sanchi,5 grams)and Rhizoma Acori Tarainowii(Tararinow Sweetflag Rhizome,10 grams).
Boiled together. 150ml of the juice,p.o.,twice a day,for 28 days
Active Comparator: A
just the current Modern Medicine therapy for stroke would be available in the arm.
250 ml Mannitol Injection or Glycerin and Fructose Injection ,once a day, for 3-5 days
Please refer to this study by its ClinicalTrials.gov identifier: NCT00569088
|Institute of Internal Intractable Diseases, Nanjing University of Traditonal Chinese Medicine|
|Nanjing, Jiangsu, China|
|Principal Investigator:||Mianhua Wu, Dr.||Nanjing Uinversity of Traditional Chinese Medicine|