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Microarray Analysis of Gene Expression and Identification of Progenitor Cells in Lung Carcinoma
The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified July 2010 by Stanford University.
Recruitment status was: Recruiting
Recruitment status was: Recruiting
Sponsor:
Stanford University
Collaborator:
TRDRP
Information provided by:
Stanford University
ClinicalTrials.gov Identifier:
NCT00568906
First received: December 4, 2007
Last updated: July 2, 2010
Last verified: July 2010
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Purpose
This study will investigate gene expression profiles in normal human lung tissue, lung carcinoma and metastatic tumor to the lung. The expression of up to 20,000 genes in a given lung tissue sample will be examined by cDNA microarray analysis and compared to normal lung tissue. In addition, we hope to identify a particular subset of lung cancer cells with an enhanced capacity for proliferation and self-renewal , analogous to the stem cells recently identified for certain types of leukemia, breast cancer and brain tumors.
| Condition |
|---|
| Carcinoma, Giant Cell Carcinoma, Non-Small-Cell Lung Lung Cancer |
| Study Type: | Observational |
| Study Design: | Observational Model: Case Control Time Perspective: Prospective |
| Official Title: | Microarray Analysis of Gene Expression and Identification of Progenitor Cells in Lung Carcinoma |
Resource links provided by NLM:
Further study details as provided by Stanford University:
Eligibility| Ages Eligible for Study: | 18 Years and older (Adult, Senior) |
| Sexes Eligible for Study: | All |
| Accepts Healthy Volunteers: | No |
| Sampling Method: | Non-Probability Sample |
Study Population
Patients who agree to participate in this study will be those who are undergoing wedge resection, lobectomy on pneumonectomy for clinically diagnosed lung carcinoma or metastatic tumors to the lung, or who are undergoing therapeutic or diagnostic thoracentesis for malignant pleural effusion.
Criteria
Inclusion Criteria:Adults with non small cell lung cancer
Exclusion Criteria:NA
Contacts and Locations
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To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below.
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00568906
Please refer to this study by its ClinicalTrials.gov identifier: NCT00568906
Contacts
| Contact: Susan Jacobs, RN | (650) 725-8082 | ssjpulm@stanford.edu |
Locations
| United States, California | |
| Stanford University School of Medicine | Recruiting |
| Stanford, California, United States, 94305 | |
| Contact: Susan Jacobs, RN 650-725-8082 ssjpulm@stanford.edu | |
| Contact: Cancer Clinical Trials Office (650) 498-7061 | |
| Principal Investigator: Glenn D. Rosen | |
| Sub-Investigator: Laurie Elizabeth Ailles | |
| Sub-Investigator: Walter B Cannon | |
| Sub-Investigator: Dr Jessica S. Donington | |
| Sub-Investigator: Cathy Shachaf | |
| Sub-Investigator: Heather A. Wakelee | |
| Sub-Investigator: Irving L. Weissman M.D. | |
| Sub-Investigator: Richard I Whyte | |
| Sub-Investigator: Tze-Ming Chen | |
| Principal Investigator: Daya Upadhyay | |
Sponsors and Collaborators
Stanford University
TRDRP
Investigators
| Principal Investigator: | Daya Upadhyay | Stanford University |
| Principal Investigator: | Glenn D. Rosen | Stanford University |
More Information
| Responsible Party: | Glenn D. Rosen, Stanford University School of Medicine |
| ClinicalTrials.gov Identifier: | NCT00568906 History of Changes |
| Other Study ID Numbers: |
SU-11062007-807 76094 LUN0011 |
| Study First Received: | December 4, 2007 |
| Last Updated: | July 2, 2010 |
Additional relevant MeSH terms:
|
Carcinoma Carcinoma, Non-Small-Cell Lung Lung Neoplasms Carcinoma, Giant Cell Neoplasms, Glandular and Epithelial Neoplasms by Histologic Type Neoplasms |
Carcinoma, Bronchogenic Bronchial Neoplasms Respiratory Tract Neoplasms Thoracic Neoplasms Neoplasms by Site Lung Diseases Respiratory Tract Diseases |
ClinicalTrials.gov processed this record on June 26, 2017