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The Specific Lung Elastance in Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS) Patients in Supine and Prone Position

This study has been completed.
Information provided by (Responsible Party):
Davide Chiumello, Policlinico Hospital Identifier:
First received: December 5, 2007
Last updated: April 27, 2015
Last verified: April 2015
The investigators aim is to study the specific lung elastance in ALI/ARDS patients during invasive mechanical ventilation, in supine and prone position.

Condition Intervention
Acute Lung Injury
Acute Respiratory Distress Syndrome
Procedure: specific elastance

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: The Specific Lung Elastance in ALI/ARDS Patients in Supine and Prone Position

Resource links provided by NLM:

Further study details as provided by Policlinico Hospital:

Primary Outcome Measures:
  • Specific elastance [ Time Frame: 5 minutes ]

Enrollment: 15
Study Start Date: December 2007
Study Completion Date: January 2015
Primary Completion Date: November 2010 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: 1 Procedure: specific elastance
The investigators study the specific lung elastance in ALI/ARDS patients in supine and prone position.

Detailed Description:
In sedated and paralyzed ALI/ARDS patients, we study and compare the specific lung elastance in supine and prone position during invasive mechanical ventilation.

Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • ALI/ARDS patients during invasive mechanical ventilation

Exclusion Criteria:

  • Haemodynamic failure, pneumothorax
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Please refer to this study by its identifier: NCT00568659

Policlinico Hospital
Milano, Italy, 20122
Sponsors and Collaborators
Policlinico Hospital
Principal Investigator: Davide Chiumello, MD Policlinico Hospital
  More Information

Responsible Party: Davide Chiumello, MD, Policlinico Hospital Identifier: NCT00568659     History of Changes
Other Study ID Numbers: 1111
Study First Received: December 5, 2007
Last Updated: April 27, 2015

Keywords provided by Policlinico Hospital:
Gas exchange
Respiratory mechanics
Ventilator Induced Lung Injury

Additional relevant MeSH terms:
Wounds and Injuries
Respiratory Distress Syndrome, Newborn
Respiratory Distress Syndrome, Adult
Acute Lung Injury
Lung Injury
Pathologic Processes
Lung Diseases
Respiratory Tract Diseases
Respiration Disorders
Infant, Premature, Diseases
Infant, Newborn, Diseases
Thoracic Injuries processed this record on April 28, 2017