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Acute Comfort and Blur of Systane and Optive

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00568386
First Posted: December 6, 2007
Last Update Posted: February 2, 2012
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Alcon Research
  Purpose
To evaluate drop comfort, acceptability, preference and blur profile between two marketed artificial tears in both dry eye and non-dry eye patient population.

Condition Intervention
Dry Eye Other: Systane Lubricant Eye Drops Other: Optive Lubricant Eye Drops

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Double
Primary Purpose: Treatment
Official Title: Acute Comfort and Blurring Profile Evaluation Comparing Systane Lubricant Eye Drops to Optive Lubricant Eye Drops

Resource links provided by NLM:


Further study details as provided by Alcon Research:

Primary Outcome Measures:
  • Visual Blur [ Time Frame: 3 minutes post dose ]
    Visual blur profile is a visual scale ranging from 0 (no blur) to 50 (most blurry). Patients were asked to rate there vision on a specific focal point (an object in the room) through 3 minutes.


Enrollment: 40
Study Start Date: November 2007
Study Completion Date: December 2007
Arms Assigned Interventions
Experimental: Systane Lubricant Eye Drops
Systane Lubricant Eye Drops 1 drop in each eye one time
Other: Systane Lubricant Eye Drops
Systane Lubricant Eye Drops 1 drop each eye once time
Active Comparator: Optive Lubricant Eye Drops
Optive Lubricant Eye Drops 1 drop each one time
Other: Optive Lubricant Eye Drops
Optive Lubricant Eye Drops 1 drop each eye one time

  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Healthy, normal eyes OR documented diagnosis of dry eye

Exclusion Criteria:

  • Must not have worn contact lenses for 7 days preceding enrollment
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00568386


Sponsors and Collaborators
Alcon Research
Investigators
Principal Investigator: Mike Christensen Alcon Research
  More Information

Responsible Party: Alcon Research
ClinicalTrials.gov Identifier: NCT00568386     History of Changes
Other Study ID Numbers: M-07-02
First Submitted: December 5, 2007
First Posted: December 6, 2007
Results First Submitted: December 18, 2008
Results First Posted: March 10, 2010
Last Update Posted: February 2, 2012
Last Verified: January 2012

Keywords provided by Alcon Research:
Dry eye

Additional relevant MeSH terms:
Ophthalmic Solutions
Tetrahydrozoline
Lubricant Eye Drops
Pharmaceutical Solutions
Sympathomimetics
Autonomic Agents
Peripheral Nervous System Agents
Physiological Effects of Drugs
Nasal Decongestants
Vasoconstrictor Agents
Respiratory System Agents


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