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Study of Effectiveness of Mexyn-A (Mexyn-A)

This study has been completed.
Information provided by:
Evangelical Synod Medical Centre Identifier:
First received: November 30, 2007
Last updated: October 16, 2013
Last verified: October 2013
Atomised Methoxymethane-in-Aqua (MEXYN-A) a new topical self-chilled, non-steroidal, non-flammable, pressurised spray which embodies in one simultaneous application, most of the currently recognised and effective chemical, mechanical and thermal anti-pruritic therapies and hydrotherapy.

Condition Intervention
Pruritus Device: Mexyn-A

Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Proof of Concept of MEXYN-A

Resource links provided by NLM:

Further study details as provided by Evangelical Synod Medical Centre:

Primary Outcome Measures:
  • Treating Pruritus [ Time Frame: three days ]

Secondary Outcome Measures:
  • measuring itch-free period after applying the new treatment, effect on sleep disturbance [ Time Frame: three days ]

Enrollment: 279
Study Start Date: March 2002
Study Completion Date: September 2005
Arms Assigned Interventions
Experimental: 1
Device: Mexyn-A
Atomised topical self-chilled pressurised spray
Other Name: Clearitch, Itcharret, itchclear, Magicool-Plus

Detailed Description:
The primary clinical endpoint was to establish MEXYN-A efficacy and safety in abolishing or reducing pruritus related to cutaneous diseases, insect bites and poison ivy, within few seconds of the application. The secondary endpoint was to measure the itch free period as a result of the new intervention.

Ages Eligible for Study:   5 Years to 80 Years   (Child, Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Patients suffering from severe itching due to : Atopic Dermatitis, contact dermatitis, psoriasis, urticaria, xerosis, prickly heat, genital pruritus, chicken pox, aquagenic pruritus, lichen planus, poison ivey, insect bites.
  • Past experience with the use of at least one conventional medication for pruritus or conventional medication for the same disorder patients suffered.

Exclusion Criteria:

  • Patients who have taken any anti-pruritic drug during the month prior to participation.
  • Patients who have taken drugs for any reason for 2 days prior to participating in the study.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00568204

Evangelical Synod Medical Centre
Cairo, Egypt, 11111
Sponsors and Collaborators
Evangelical Synod Medical Centre
Principal Investigator: Ihab Akhnoukh Evangelical Synod Medical Centre
Study Director: Ashraf Khella Harpur Memorial Hospital
  More Information

Responsible Party: Dr Ihab Akhnoukh M.D., Evangelical Synod Medical Centre Identifier: NCT00568204     History of Changes
Other Study ID Numbers: EvangelicalSynodMC
Study First Received: November 30, 2007
Last Updated: October 16, 2013

Keywords provided by Evangelical Synod Medical Centre:
pruritus, itching, mexyn-a, clearitch, magicool-plus

Additional relevant MeSH terms:
Skin Diseases
Skin Manifestations
Signs and Symptoms processed this record on June 23, 2017