Co-Infection of NTM in Patients With Smear Positive Pulmonary TB

This study has been completed.
Information provided by:
Seoul National University Hospital Identifier:
First received: December 2, 2007
Last updated: June 20, 2009
Last verified: June 2009
The aim of this study is to elucidate the prevalence of nontuberculous mycobacterial (NTM) co-infection in patients with smear positive pulmonary TB. To detect the NTM co-infection, we will perform duplex PCR targeted for mycobacterial hsp 65 gene using sputa. In addition, the clinical significance of this co-infection will be evaluated.

Tuberculosis, Pulmonary

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Detection of Nontuberculous Mycobacterial co-Infection Using Duplex PCR for Mycobacterial Hsp 65 Gene and Its Clinical Significance in Patients With Smear Positive Pulmonary Tuberculosis

Resource links provided by NLM:

Further study details as provided by Seoul National University Hospital:

Biospecimen Retention:   Samples Without DNA
Sputa with positive AFB smear

Estimated Enrollment: 200
Study Start Date: December 2007
Study Completion Date: December 2008
Primary Completion Date: December 2008 (Final data collection date for primary outcome measure)

Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients visited Seoul National University Hospital

Inclusion Criteria:

  • New patients with pulmonary TB
  • Sputum AFB smear-positivity

Exclusion Criteria:

  • Non-applicable
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00567151

Korea, Republic of
Seoul National University Hospital
Seoul, Korea, Republic of, 110-744
Sponsors and Collaborators
Seoul National University Hospital
Principal Investigator: Jae-Joon Yim, MD Seoul National Univeristy Hospital
  More Information

No publications provided

Responsible Party: Jae-Joon Yim/Associate Professor, Division of Pulmonary and Critical Care Medicine, Seoul National University Hospital Identifier: NCT00567151     History of Changes
Other Study ID Numbers: H-0711-022-225, Non-applicable
Study First Received: December 2, 2007
Last Updated: June 20, 2009
Health Authority: South Korea: Institutional Review Board

Additional relevant MeSH terms:
Tuberculosis, Pulmonary
Actinomycetales Infections
Bacterial Infections
Gram-Positive Bacterial Infections
Lung Diseases
Mycobacterium Infections
Respiratory Tract Diseases
Respiratory Tract Infections processed this record on November 27, 2015