Continuous Infusion of Dexamethasone Plus Tramadol Adjunct to Morphine PCA After Abdominal Hysterectomy (DTMPCA)
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|ClinicalTrials.gov Identifier: NCT00564603|
Recruitment Status : Completed
First Posted : November 28, 2007
Last Update Posted : April 21, 2008
|Condition or disease||Intervention/treatment||Phase|
|Postoperative Pain Post Operative Analgesia Patient-Controlled Analgesia Abdominal Surgeries||Drug: Dexamethasone Sodium Phosphate Injection Other: 0.9% Saline||Phase 4|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||300 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)|
|Official Title:||Intravenous Continuous Infusion of Dexamethasone Plus Tramadol Combined With Standard Morphine Patient-Controlled Analgesia After Total Abdominal Hysterectomy|
|Study Start Date :||August 2007|
|Actual Primary Completion Date :||November 2007|
|Actual Study Completion Date :||November 2007|
Placebo Comparator: 1
Saline with same volume added to tramadol infusion combined with morphine PCA.
Other: 0.9% Saline
Saline, in same volume of 2mL
Active Comparator: 2
Dexamethasone 10mg in 2mL added to tramadol infusion adjunct to morphine PCA.
Drug: Dexamethasone Sodium Phosphate Injection
Dexamethasone, 10mg, continuously infused up to 48h after surgeries.
- Visual analog scale (VAS) of pain [ Time Frame: 0-48h after surgeries ]
- First requirement of morphine; Total morphine consumption; VAS sedation; VAS satisfaction; Side effects; Overall conditions of patients; [ Time Frame: 0-48h after surgeries ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00564603
|Nanjing Maternal and Child Care Hospital|
|Nanjing, Jiangsu, China, 210004|
|Study Director:||XiaoFeng Shen, MD||Nanjing Medical University|