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Evaluation of Retinal Structure With High Resolution Optical Coherence Tomography (OCT)

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ClinicalTrials.gov Identifier: NCT00564291
Recruitment Status : Recruiting
First Posted : November 27, 2007
Last Update Posted : May 3, 2018
Sponsor:
Collaborator:
University of Bern
Information provided by (Responsible Party):
Sebastian Wolf, University Hospital Inselspital, Berne

Brief Summary:
Comparison of different OCT instruments to assess retinal thickness, correlation to fluorescein angiography, and visual outcome after therapy with anti-VEGF therapy

Condition or disease Intervention/treatment
Macular Edema CNV Other: Examination with an OCT device

Detailed Description:
Comparison of different OCT instruments to assess retinal thickness, correlation to fluorescein angiography, and visual outcome after therapy with anti-VEGF therapy

Study Type : Observational
Estimated Enrollment : 700 participants
Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Evaluation of Retinal Structure With High Resolution OCT
Actual Study Start Date : January 2007
Estimated Primary Completion Date : November 2019
Estimated Study Completion Date : November 2020

Group/Cohort Intervention/treatment
1
Healthy volunteers
Other: Examination with an OCT device
2
CSME secondary to diabetic retinopathy
3
ARMD with CNV before and after therapy
Other: Examination with an OCT device
4
ARMD atrophic
Other: Examination with an OCT device
5
Retinal vein occlusion
Other: Examination with an OCT device
6
retinitis pigmentosa
Other: Examination with an OCT device
7
vitreoretinal proliferation
Other: Examination with an OCT device



Primary Outcome Measures :
  1. Integrity of retinal layers [ Time Frame: End of study ]


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Ages Eligible for Study:   18 Years to 100 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
healthy subjects and patients with macular diseases
Criteria

Inclusion Criteria:

  • Macular disease
  • Healthy subjects

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00564291


Contacts
Contact: Sebastian Wolf, MD, PhD sebastian.wolf@insel.ch

Locations
Switzerland
Dep. Ophthalmology, University Hospital Bern Recruiting
Bern, Switzerland, 3010
Contact: Sebastian Wolf, MD PhD       sebastian.wolf@insel.ch   
Sub-Investigator: Martin Zinkernagel, MD PhD         
Sub-Investigator: Andreas Ebneter, MD         
Sub-Investigator: Marion Munk, MD         
Klinik und Poliklinik für Augenheilkunde, University Bern Recruiting
Bern, Switzerland
Principal Investigator: Ute Wolf-Schnurrbusch, MD         
Sponsors and Collaborators
Sebastian Wolf
University of Bern
Investigators
Principal Investigator: Sebastian Wolf, MD, PhD University of Bern
Study Director: Sebastian Wolf, MD PhD University of Bern

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Sebastian Wolf, Director, University Hospital Inselspital, Berne
ClinicalTrials.gov Identifier: NCT00564291     History of Changes
Other Study ID Numbers: KEK 044/07
First Posted: November 27, 2007    Key Record Dates
Last Update Posted: May 3, 2018
Last Verified: May 2018

Keywords provided by Sebastian Wolf, University Hospital Inselspital, Berne:
OCT

Additional relevant MeSH terms:
Macular Edema
Macular Degeneration
Retinal Degeneration
Retinal Diseases
Eye Diseases