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Change of Neural Network Indicators Through Narrative Treatment of PTSD in Torture Victims

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ClinicalTrials.gov Identifier: NCT00563888
Recruitment Status : Unknown
Verified November 2007 by University of Konstanz.
Recruitment status was:  Active, not recruiting
First Posted : November 26, 2007
Last Update Posted : November 26, 2007
Sponsor:
Collaborator:
Information provided by:

Study Description
Brief Summary:
Effective Treatment of PTSD involves talking about the traumatic event in detail.It is unclear how this process influences the sensory-specific trauma network (fear structure)in the traumatized person. The goal of the project is to test the hypothesis that treatment-facilitated recovery does not change the original fear structure but establishes an inhibitory mechanism that depends on verbal activity. An affective visual steady-state paradigm in magnetencephalography (MEG) using positive, aversive and neutral picture stimuli will be used to examine the spatial and temporal pattern of the processing of emotional stimuli. To examine the effects of treatment this paradigm will be used as outcome measure within a randomized controlled trial of Narrative Exposure Therapy and a waiting-list control condition for severely traumatized torture victims.

Condition or disease Intervention/treatment
PTSD Behavioral: NET

Study Design

Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 30 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Change of Neural Network Indicators Through Narrative Treatment of PTSD in Torture Victims
Study Start Date : January 2007
Estimated Study Completion Date : December 2008
Arms and Interventions

Arm Intervention/treatment
Experimental: A
Narrative Exposure Therapy (NET)
Behavioral: NET
Narrative Exposure Therapy for traumatized survivors of organized violence
No Intervention: B
Waitinglist Control Group


Outcome Measures

Primary Outcome Measures :
  1. PTSD diagnosis and severity score according to the Clinicians Administered PTSD Scale (CAPS) [ Time Frame: 4 & 9 months after completion of treatment ]

Secondary Outcome Measures :
  1. steady state visual evoked magnetic fields in response to affective stimuli [ Time Frame: 4 & 9 months after completion of treatment ]

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 65 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • experiences of organized violence/torture
  • PTSD diagnosis

Exclusion Criteria:

  • psychotic disorder
  • neurological disease or seizures
  • current drug/alcohol abuse
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00563888


Locations
Germany
University of Konstanz, Department of Psychology
Konstanz, Germany, 78467
Sponsors and Collaborators
University of Konstanz
German Research Foundation
Investigators
Study Director: Claudia Catani, Dr. University of Konstanz
Principal Investigator: Frank Neuner, Prof. University of Konstanz