Benefit of Adding Chemotherapy And/Or Modification of Radiotherapy Schedule for Advance Nasopharyngeal Carcinoma (T3-4N0-1M0)
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Ages Eligible for Study:
up to 70 Years (Child, Adult, Older Adult)
Sexes Eligible for Study:
Undifferentiated or non-keratinizing carcinoma
Tumor staged as T3-4 AND N0-1
No evidence of distant metastasis (M0)
Performance status: 0-2
Marrow: WBC >= 4 and platelet = 100
Renal: creatinine clearance = 60
WHO type I squamous cell carcinoma or adenocarcinoma
Age >= 70
Palliative intent or tumor extent mandating AP opposing facio-cervical fields
Prior malignancy except adequately treated basal cell or squamous cell skin cancer, in situ cervical cancer, or other cancer for which the patient has been disease-free for 5 years
Keywords provided by Hospital Authority, Hong Kong:
Additional relevant MeSH terms:
Nasopharyngeal Neoplasms Neoplasms, Glandular and Epithelial Neoplasms by Histologic Type Neoplasms
Head and Neck Neoplasms Neoplasms by Site Nasopharyngeal Diseases Neoplasms, Squamous Cell
Carcinoma, Squamous Cell