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A Comparative Study of the Efficacy of Transcatheter Arterial Chemoembolization (TACE) and Transcatheter Arterial Pegylated Interferon Embolization (TAIE) for Liver Cancer

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified July 2010 by Hospital Authority, Hong Kong.
Recruitment status was:  Recruiting
Information provided by:
Hospital Authority, Hong Kong Identifier:
First received: November 21, 2007
Last updated: July 6, 2010
Last verified: July 2010

Primary: To compare the efficacy of TACE and TAIE.

Secondary: To compare the side effects of TACE and TAIE.

The outcome measurements include survival benefit and tumour regression induced by the two therapies.

Condition Intervention
Carcinoma, Hepatocellular
Procedure: Transcatheter Arterial Chemoembolization (TACE)
Procedure: Transcatheter Arterial Pegylated Interferon Embolization (TAIE)

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: A Comparative Study of the Efficacy of Transcatheter Arterial Chemoembolization (TACE) and Transcatheter Arterial Pegylated Interferon Embolization (TAIE) for Hepatocellular Carcinoma

Resource links provided by NLM:

Further study details as provided by Hospital Authority, Hong Kong:

Primary Outcome Measures:
  • regression of tumour size [ Time Frame: assessment every 6 months ]

Secondary Outcome Measures:
  • side effects [ Time Frame: every treatment given every 8 - 12 weeks ]

Estimated Enrollment: 100
Study Start Date: March 2004
Estimated Study Completion Date: December 2008

Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All

Inclusion Criteria:

  • Confirmed hepatocellular carcinoma not suitable for surgery

Exclusion Criteria:

  • Portal vein thrombosis
  • Severe arteriovenous shunt
  • Bilirubin level > 50 umol/mL
  • Prothrombin time > 5 seconds
  Contacts and Locations
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Please refer to this study by its identifier: NCT00563095

Contact: Man Fung Yuen, Prof (852) 2855 5311

Queen Mary Hospital Recruiting
Hong Kong, China
Sub-Investigator: Ching Lung Lai, Prof         
Sub-Investigator: Clara Ooi, Prof         
Sponsors and Collaborators
Hospital Authority, Hong Kong
Principal Investigator: Man Fung Yuen, Prof Department of Medicine, Queen Mary Hospital/ The University of Hong Kong
  More Information

Additional Information: Identifier: NCT00563095     History of Changes
Other Study ID Numbers: EC 1942-02
Study First Received: November 21, 2007
Last Updated: July 6, 2010

Keywords provided by Hospital Authority, Hong Kong:
Hepatocellular carcinoma

Additional relevant MeSH terms:
Carcinoma, Hepatocellular
Neoplasms, Glandular and Epithelial
Neoplasms by Histologic Type
Liver Neoplasms
Digestive System Neoplasms
Neoplasms by Site
Digestive System Diseases
Liver Diseases
Antineoplastic Agents
Antiviral Agents
Anti-Infective Agents processed this record on May 25, 2017