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Study of Inhaled Glucocorticosteroid Administration in Asthma Patients

This study has been completed.
Information provided by:
Hamamatsu University Identifier:
First received: November 15, 2007
Last updated: March 13, 2009
Last verified: March 2009
Once-daily inhaled glucocorticosteroids treatment can sufficiently control airway inflammation in asthma patients.

Condition Intervention Phase
Drug: Budesonide,hydrofluoroalkane-beclomethasone dipropionate
Drug: Budesonide,hydrofluoroalkane-beclomethasone
Phase 4

Study Type: Observational
Study Design: Observational Model: Case-Crossover
Time Perspective: Cross-Sectional
Official Title: Phase 4 Study of Once-Daily Inhaled Glucocorticosteroid Administration in Asthma Patients

Resource links provided by NLM:

Further study details as provided by Hamamatsu University:

Primary Outcome Measures:
  • once-daily administration of inhaled glucocorticosteroids can control airway inflammation [ Time Frame: two-year ]

Enrollment: 24
Study Start Date: November 2005
Study Completion Date: March 2007
Groups/Cohorts Assigned Interventions
receive once-daily administration of inhaled glucocorticosteroids at bedtime
Drug: Budesonide,hydrofluoroalkane-beclomethasone
once-daily administration at bedtime
receive twice-daily administration of inhaled glucocorticosteroids
Drug: Budesonide,hydrofluoroalkane-beclomethasone dipropionate
receive twice-daily administration


Ages Eligible for Study:   20 Years to 80 Years   (Adult, Senior)
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
University Hospital

Inclusion Criteria:

  • Receive ICS for one year or more, with no change in dose within the previous 8 weeks

Exclusion Criteria:

  • Two or more courses of oral corticosteroid in the previous 12 months
  • Admission to hospital due to asthma in the previous 6 months
  • Admission to the intensive care unit due to asthma at any time in the past
  • Current cigarette smoker.
  Contacts and Locations
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Please refer to this study by its identifier: NCT00559689

Hamamatsu University School of Medicine
Hamamatsu, Japan, 431-3192
Sponsors and Collaborators
Hamamatsu University
Study Chair: Kingo Chida, MD,PhD
  More Information Identifier: NCT00559689     History of Changes
Other Study ID Numbers: Hamamatsu-17-43  H-17-43 
Study First Received: November 15, 2007
Last Updated: March 13, 2009
Health Authority: Japan: Institutional Review Board

Keywords provided by Hamamatsu University:
asthma patients

Additional relevant MeSH terms:
Bronchial Diseases
Respiratory Tract Diseases
Lung Diseases, Obstructive
Lung Diseases
Respiratory Hypersensitivity
Hypersensitivity, Immediate
Immune System Diseases
Anti-Inflammatory Agents
Bronchodilator Agents
Autonomic Agents
Peripheral Nervous System Agents
Physiological Effects of Drugs
Anti-Asthmatic Agents
Respiratory System Agents
Hormones, Hormone Substitutes, and Hormone Antagonists processed this record on October 21, 2016