Evaluating Electrocardiogram (ECG) Abnormalities From Young Adulthood Through Middle Age (CARDIA ECG)
|ClinicalTrials.gov Identifier: NCT00556751|
Recruitment Status : Completed
First Posted : November 12, 2007
Last Update Posted : February 18, 2016
|Condition or disease|
An ECG is a test that detects and records the electrical activity of the heart. As a diagnostic tool, it can detect and locate the source of heart problems, including heart attacks, irregular heart beats, cardiovascular disease, or other abnormalities of the heart. An ECG procedure involves attaching electrodes to the skin on the chest, arms, and legs while the electrodes detect electrical signals of the heart, and a machine displays the signals on a computer screen and graph paper. An ECG may be a beneficial way to detect cardiovascular disease because it is a low-cost and non-invasive test that is widely available in the clinical setting.
This study will examine ECGs and other study data from participants in the Coronary Artery Risk Development in Young Adults (CARDIA) study. As ECG abnormalities typically begin to develop in young adults, the CARDIA participants will provide researchers with an excellent study population. As part of the CARDIA study, ECGs were obtained from participants at baseline, and Years 7 and 20. Study researchers will use state-of-the-art technology and standardized Minnesota Code and Novacode methods to electronically code participants' ECGs and accomplish the following: 1) assess the frequency of ECG abnormalities in young adults of different races; 2) examine potential risk factors for the development and progression of ECG abnormalities; 3) investigate the relationship between ECG abnormalities and other measures of heart disease; and 4) assess differences in the frequency and patterns of ECG abnormalities between different racial groups. Study researchers will also analyze additional CARDIA study data, including cardiovascular disease risk factors, measures of atherosclerosis, and echocardiographic ultrasound pictures of the heart.
This research will provide important insights into the ways in which ECG abnormalities are associated with increased risk for cardiovascular disease and how the risk may differ between blacks and whites. Results from this study may ultimately lead to improvements in preventive strategies for cardiovascular disease in young adults.
|Study Type :||Observational|
|Actual Enrollment :||5115 participants|
|Official Title:||Epidemiology and Mechanisms of ECG Abnormalities: Young Adulthood to Middle Age|
|Study Start Date :||January 1985|
|Study Completion Date :||September 2006|
- Development of resting ECG abnormalities, specifically isolated non-specific ST-segment and T-wave abnormalities [ Time Frame: Measured at Years 7 and 20 ]
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00556751
|United States, Illinois|
|Chicago, Illinois, United States, 60611|
|Principal Investigator:||Donald M. Lloyd-Jones, MD, ScM||Northwestern University Feinberg School of Medicine|