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Salivary Catecholamines in Aphthous Stomatitis (Canker Sores)

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ClinicalTrials.gov Identifier: NCT00556686
Recruitment Status : Withdrawn (We are currently modifying the study)
First Posted : November 12, 2007
Last Update Posted : April 22, 2015
Sponsor:
Information provided by (Responsible Party):

Study Description
Brief Summary:
The purpose of this study is to examine how compounds produced in patients with canker sores affect wound healing.

Condition or disease
Canker Sore

Detailed Description:
The purpose of this study is to determine if salivary catecholamines are elevated in patients with the disease aphthous stomatitis. The results of this study will be combined with those performed in collaboration with a co-Investigator to understand the effects of catecholamines on mucosal wound healing and oral epithelial cell migration.

Study Design

Study Type : Observational
Actual Enrollment : 0 participants
Observational Model: Case Control
Time Perspective: Prospective
Official Title: Salivary Catecholamines in Aphthous Stomatitis
Study Start Date : August 2006
Estimated Primary Completion Date : December 2009
Estimated Study Completion Date : December 2009

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Canker Sores
U.S. FDA Resources

Groups and Cohorts

Group/Cohort
1
Individuals with a history of canker sores.
2
Individuals with no history of canker sores.


Outcome Measures

Biospecimen Retention:   Samples Without DNA
saliva

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
All subjects will be sampled from the community.
Criteria

Inclusion Criteria:

  • Age 18 or older, both genders
  • History of recurrent aphthous ulcers with 4 or more episodes per year

Exclusion Criteria:

  • History of salivary gland disease including Sjogren's disease, parotitis, and sialolithiasis
  • History of benign or malignant salivary gland tumor
  • History of celiac disease, ulcerative colitis or Crohn's disease
  • Patients on medications that affect salivary flow such as anti-depressants and anti-cholinergic medications
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00556686


Sponsors and Collaborators
University of California, Davis
Investigators
Principal Investigator: Nasim Fazel, MD, DDS University of California, Davis
More Information

Additional Information:
Responsible Party: University of California, Davis
ClinicalTrials.gov Identifier: NCT00556686     History of Changes
Other Study ID Numbers: 200614581
First Posted: November 12, 2007    Key Record Dates
Last Update Posted: April 22, 2015
Last Verified: April 2015

Additional relevant MeSH terms:
Stomatitis
Stomatitis, Aphthous
Mouth Diseases
Stomatognathic Diseases