Does Aldosterone Cause Hypertension by a Non-Renal Mechanism?
|ClinicalTrials.gov Identifier: NCT00553722|
Recruitment Status : Unknown
Verified October 2007 by Shaare Zedek Medical Center.
Recruitment status was: Not yet recruiting
First Posted : November 6, 2007
Last Update Posted : November 6, 2007
|Condition or disease||Intervention/treatment||Phase|
|Hypertension Dialysis Hyperaldosteronism||Drug: Eplerenone Drug: Placebo||Phase 4|
Show Detailed Description
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||27 participants|
|Intervention Model:||Crossover Assignment|
|Masking:||Triple (Participant, Care Provider, Investigator)|
|Official Title:||Does Aldosterone Cause Hypertension by a Non-Renal Mechanism?|
|Study Start Date :||November 2007|
|Estimated Study Completion Date :||November 2009|
Administer Eplerenone, 25 mg, orally twice daily for 4 weeks.
Administer Eplerenone, 25 mg,orally twice daily for 4 weeks.
Placebo Comparator: placebo
Administer a placebo tablet orally twice daily for 4 weeks
Administer a placebo tablet orally twice daily for 4 weeks.
- Significant drop in blood pressure with Eplerenone when compared to placebo. [ Time Frame: days ]
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00553722
|Contact: Linda Shavit, MD||02 firstname.lastname@example.org|
|Contact: Itzchak Slotki, MD||o2 email@example.com|
|Shaare Zedek Medical Center||Not yet recruiting|
|Jerusalem, Israel, 91031|
|Contact: Linda Shavit, MD 02 6555086 firstname.lastname@example.org|
|Principal Investigator: Linda Shavit, MD|
|Principal Investigator:||Linda Shavit, MD||Shaare Zedek Medical Center|