Mechanism and Predictor of Side Branch Jailing (PRESSURE)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00553670
Recruitment Status : Completed
First Posted : November 5, 2007
Last Update Posted : March 30, 2011
Information provided by:
Seoul National University Hospital

Brief Summary:
Coronary artery bifurcation lesion is still one of the most challenging lesion subsets in the field of non-surgical treatment for a stenotic coronary artery. When one stent is placed in the main brach, it increases the side branch's stenosis degree. However, its mechanism and incidence are not known. This study will be performed to search for the mechanism and incidence of that phenomenon.

Condition or disease
Bifurcating Coronary Artery Lesions Main Branch Stent Implantation Side Branch Jailing

Study Type : Observational
Estimated Enrollment : 100 participants
Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Predictor and Mechanism of a Side Branch Jail After Main Branch Stent Implantation in Bifurcation Lesions
Study Start Date : November 2007
Actual Study Completion Date : May 2009

Patients with elective coronary intervention for LAD-diagonal bifurcation lesion with provisional side branch intervention strategy with successful intravascular ultrasound and fractional flow reserve measurement

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Ages Eligible for Study:   18 Years to 80 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients with bifurcating coronary artery lesion in left anterior descending coronary artery

Inclusion Criteria:

  1. Elective coronary intervention (including stabilized ACS patients)
  2. Bifurcation lesion with TIMI 3 flow
  3. Side branch diameter > 2mm, side branch lesion length < 10mm by visual estimation

Exclusion Criteria:

  1. Left main coronary disease
  2. AMI, or Old MI at LAD territory
  3. LVEF < 40%, or other significant valvular or myocardial disease
  4. Significant side branch distal lesion
  5. Angiographically visible thrombus
  6. Heavily calcified lesion
  7. Side branch predilatation before main branch stent implantation

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00553670

Korea, Republic of
Seoul national university hospital
Seoul, Korea, Republic of, 110744
Sponsors and Collaborators
Seoul National University Hospital
Study Director: Bon-Kwon Koo, PhD Seoul National University Hospital

Publications automatically indexed to this study by Identifier (NCT Number): Identifier: NCT00553670     History of Changes
Other Study ID Numbers: H-0707-022-212
First Posted: November 5, 2007    Key Record Dates
Last Update Posted: March 30, 2011
Last Verified: March 2011

Keywords provided by Seoul National University Hospital:
coronary artery
intravascular ultrasound
fractional flow reserve