The Relation Between Periodontal Disease and Metabolic Syndrome

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00553007
Recruitment Status : Unknown
Verified October 2007 by Aichi Gakuin University.
Recruitment status was:  Recruiting
First Posted : November 2, 2007
Last Update Posted : November 2, 2007
Information provided by:
Aichi Gakuin University

Brief Summary:
Periodontal disease is associated with the components of Metabolic syndrome, such as obesity, diabetes, hypertension and hyperlipidemia. Therefore, strong relation with periodontal disease and metabolic syndrome is suggested. the overall goal of this study is to define the relation between periodontal disease and metabolic syndrome, including atherosclerosis.

Condition or disease Intervention/treatment Phase
Periodontal Disease Metabolic Syndrome Procedure: Periodontal therapy Not Applicable

Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 80 participants
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: The Relation Between Periodontal Disease and Metabolic Syndrome
Study Start Date : October 2007
Estimated Study Completion Date : October 2009

Intervention Details:
  • Procedure: Periodontal therapy
    Normal periodontal therapy is performed.

Primary Outcome Measures :
  1. features of periodontal disease and metabolic syndrome [ Time Frame: one year ]

Secondary Outcome Measures :
  1. Pulse wave velocity; max Intima-Media Thickness(IMT); mean IMT; ankle-brachial blood pressure index; toe-brachial blood pressure index [ Time Frame: one year ]

Information from the National Library of Medicine

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Ages Eligible for Study:   20 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Patients with periodontal disease

Exclusion Criteria:

  • Patients with malignant disease
  • Pregnant women

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00553007

Contact: Tatsuaki Matsubara, MD, PhD +81-52-759-2111

Aichi Gakuin University Recruiting
Nagoya, Aichi, Japan, 464-8651
Sponsors and Collaborators
Aichi Gakuin University
Principal Investigator: Tatsuaki Matsubara, MD. PhD Aichi Gakuin University Identifier: NCT00553007     History of Changes
Other Study ID Numbers: AGU070001
First Posted: November 2, 2007    Key Record Dates
Last Update Posted: November 2, 2007
Last Verified: October 2007

Keywords provided by Aichi Gakuin University:
Periodontal disease
Metabolic Syndrome

Additional relevant MeSH terms:
Metabolic Syndrome X
Periodontal Diseases
Gingival Diseases
Pathologic Processes
Insulin Resistance
Glucose Metabolism Disorders
Metabolic Diseases
Mouth Diseases
Stomatognathic Diseases