Pulmonary Function at Presentation and Follow-up in Hemato-Oncology 3-7 Years Old Children
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|ClinicalTrials.gov Identifier: NCT00552825|
Recruitment Status : Completed
First Posted : November 2, 2007
Last Update Posted : November 2, 2007
|Condition or disease|
|Acute Lymphoblastic Leukemia Acute Myeloblastic Leukemia Solid Tumors, Hodgkin's Disease Non-Malignant|
Pulmonary function tests (PFTs) are a part of the routine follow-up of patients receiving anti-cancer treatment. Treatment is frequently associated with diverse pulmonary damage which may become functionally and clinically evident many years later. PFTs may help to quantify the damage in the lungs; help to evaluate the point at which lung function deviates from normal to allow early intervention before irreversible lung damage occurs and thereby to reduce morbidity and mortality.
Reliable PFTs in the preschool age have traditionally been difficult to perform, but recent publications have demonstrated that the majority of preschool children can produce reproducible forced expiratory flow volume (FEVC) curves with proper coaching techniques. This recent development may enable studying the long term effect (years) of treatment on lung function in young children suffering from hemato-oncologic diseases.
|Study Type :||Observational|
|Actual Enrollment :||35 participants|
|Official Title:||Pulmonary Function at Presentation and Follow-up in Hemato-Oncology 3-7 Years|
|Study Start Date :||October 2005|
|Actual Study Completion Date :||October 2006|
all were in a single group
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00552825
|Sheba Medical CenterPediatric pulmonary unit, Pulmonary function laboratory|
|Ramat-Gan, Ramat Gan, Israel, 52621|
|Principal Investigator:||Ori Efrati, MD||Sheba Medical Center|