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Translating Research Into Practice for Postpartum Depression (TRIPPD)

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified October 2007 by Olmsted Medical Center.
Recruitment status was:  Recruiting
Information provided by:
Olmsted Medical Center Identifier:
First received: October 22, 2007
Last updated: December 3, 2007
Last verified: October 2007

This is a study to assess the impact of introducing screening and planned follow up for postpartum depression. All women ages 18 to 45 who speak English or Spanish who come to the enrolled community family medicine offices will either be given usual care or screened using the Edinburgh Postnatal Depression Screening tool. If the EDPS score is high the women will be given the PHQ-9 to more clearly identify the specific likelihood of being depressed. Women who are determined to be depressed will be treated with medication or counseling based on the preference of the women and their physicians. Women will be followed through nurse initiated phone calls and visits to the physicians office.

Outcomes include the level of depression symptoms, measure of comfort with parenting, and satisfaction with partner relationships comparing baseline levels with those at 6 and 12 months from the usual care and intervention sites. These data will be collected by questionnaire. In addition, with the women's permission, medical records will be reviewed.

Condition Intervention
Postpartum Depression Behavioral: Screening and follow up Behavioral: Usual care

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double (Participant, Outcomes Assessor)
Primary Purpose: Screening
Official Title: Practice Based Clinical Trial of Screening, Diagnosis and Follow up Management for Postpartum Depression in Family Medicine Practices.

Resource links provided by NLM:

Further study details as provided by Olmsted Medical Center:

Primary Outcome Measures:
  • Level of depressive symptoms and level of parenting comfort [ Time Frame: 12 months postpartum ]

Secondary Outcome Measures:
  • Percent eligible women screened and of those screen positive, percent treated and followed according to protocol [ Time Frame: 12 months for each women ]

Estimated Enrollment: 3000
Study Start Date: September 2005
Estimated Study Completion Date: August 2010
Arms Assigned Interventions
Experimental: 1
Intervention arm
Behavioral: Screening and follow up
Two stage screening with EPDS and PHQ-9, treatment for depression at physician's discretion and follow up phone calls and visits
Placebo Comparator: 2
Usual care
Behavioral: Usual care
usual care for identification and management of postpartum depression

Detailed Description:

A randomized controlled trial of screening and management of postpartum depression that includes a second phase assessing the maintenance of the intervention in the original intervention sites and a switch from usual care to intervention in the control sites.

Planned enrollment includes 29 family medicine practices and 3000 women over a period of four years. All follow up and management is initiated within the family medicine practices to improve generalizability and likelihood for dissemination.

In addition to the patient centered outcomes, exploratory analyses will look at the uptake and degree of implementation and maintenance of the intervention based on characteristics of the practice including size, location, affiliation with larger group, type of practice and whether or not the practice is a community health center or residency practice.


Ages Eligible for Study:   18 Years to 45 Years   (Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • 5 to 12 weeks postpartum
  • Able to speak and read English or Spanish

    • 18 to 45 years of age

Exclusion Criteria:

  • Significant cognitive impairment and unable to answer screening questions
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00548743

Contact: Barbara P Yawn, MD MSc 507 287 2758
Contact: Susan M Bertram, RN MSN 888 292 7164

United States, Minnesota
Olmsted Medical Center Recruiting
Rochester, Minnesota, United States, 55904
Principal Investigator: Barbara P Yawn, MD MSc         
Sponsors and Collaborators
Olmsted Medical Center
Principal Investigator: Barbara P Yawn, MD MSc Olmsted Medical Center
  More Information

Additional Information: Identifier: NCT00548743     History of Changes
Other Study ID Numbers: 5R01HS014744-02 ( U.S. AHRQ Grant/Contract )
Study First Received: October 22, 2007
Last Updated: December 3, 2007

Keywords provided by Olmsted Medical Center:
Dyad satisfaction
Parenting comfort
Follow up
Primary care
Practice based research

Additional relevant MeSH terms:
Depressive Disorder
Depression, Postpartum
Behavioral Symptoms
Mood Disorders
Mental Disorders
Puerperal Disorders
Pregnancy Complications processed this record on September 21, 2017